Ten Years of Progress in GW/P Body Research

  • Edward K. L. Chan
  • Marvin J. Fritzler

Part of the Advances in Experimental Medicine and Biology book series (volume 768)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Marvin J. Fritzler, Edward K. L. Chan
    Pages 5-21
  3. Saumya Jain, Roy Parker
    Pages 23-43
  4. Minoru Satoh, Jason Y. F. Chan, Angela Ceribelli, Monica Vazquez del-Mercado, Edward K. L. Chan
    Pages 45-59
  5. Donald B. Bloch, Rita A. Nobre, Wei-Hong Yang
    Pages 61-70
  6. Bing Yao, Songqing Li, Edward K. L. Chan
    Pages 71-96
  7. Sooncheol Lee, Shobha Vasudevan
    Pages 97-126
  8. Jing Li, Tom C. Hobman, Andrew J. Simmonds
    Pages 127-145
  9. Joerg E. Braun, Eric Huntzinger, Elisa Izaurralde
    Pages 147-163
  10. Chyi-Ying A. Chen, Ann-Bin Shyu
    Pages 183-195
  11. Georg Stoecklin, Nancy Kedersha
    Pages 197-211
  12. Edward K. L. Chan, Bing Yao, Marvin J. Fritzler
    Pages 261-270
  13. Back Matter
    Pages 271-276

About this book


GW bodies are novel cytoplasmic foci that were discovered and named by Dr. Chan’s group in 2002. These bodies are now known to be active cytoplasmic foci involved with the new gene regulation process mediated by microRNA that leads to translational repression and mRNA degradation. The detailed biological functions of these cytoplasmic structures are still being uncovered and the idea for this book is to provide the history of the discovery and the major work from different laboratories that has led to the characterization and elucidation of the structure and function of these new multiple subcellular structures.

Editors and affiliations

  • Edward K. L. Chan
    • 1
  • Marvin J. Fritzler
    • 2
  1. 1.College of Dentistry, Department of Oral BiologyUniversity of FloridaGainesvilleUSA
  2. 2.Dept. Medicine & Medical BiochemistryUniversity of CalgaryCalgaryCanada

Bibliographic information

Industry Sectors
Health & Hospitals