Caveolins in Cancer Pathogenesis, Prevention and Therapy

  • Isabelle Mercier
  • Jean-François Jasmin
  • Michael P. Lisanti

Part of the Current Cancer Research book series (CUCR)

Table of contents

  1. Front Matter
    Pages i-xi
  2. T. C. Thompson, S. A. Tahir, L. Li, M. Watanabe, K. Naruishi, G. Yang et al.
    Pages 1-15
  3. Andrew F. G. Quest, Vicente A. Torres, Diego A. Rodriguez, Jorge Gutierrez-Pajares, Julio C. Tapia
    Pages 17-41
  4. David W. Rittenhouse, Oeendree Mukherjee, Nathan G. Richards, Charles J. Yeo, Agnieszka K. Witkiewicz, Jonathan R. Brody
    Pages 43-52
  5. Rebecca Senetta, Paola Cassoni
    Pages 53-64
  6. Alessandra Carè, Isabella Parolini, Federica Felicetti, Massimo Sargiacomo
    Pages 65-74
  7. Grzegorz Sowa
    Pages 75-90
  8. Gloria Bonuccelli, Michael P. Lisanti
    Pages 91-104
  9. Isabelle Mercier, Michael P. Lisanti
    Pages 105-119
  10. Back Matter
    Pages 121-123

About this book


For more than a decade, caveolin proteins have attracted a lot of attention in the field of cancer research. Additional roles besides maintaining the structural integrity of caveolae (meaning “little caves” in latin) have been attributed to these complex proteins. In fact, they have emerged as important regulators of cell signaling, proliferation, invasion and angiogenesis. The current book focuses on caveolin-1, the best-studied and well- characterized of all three caveolin family members (caveolin-1, -2 and -3). As such, the current chapters illustrate the roles of caveolin-1 in breast, prostate, skin, colon, brain and pancreatic cancers, and highlight its specific contribution to tumor growth through epithelial and stromal interactions, as well as its involvement in angiogenesis. This book summarizes the existing literature and provides interesting new perspectives on future advancement and therapeutic possibilities involving caveolins in cancer. This work brings together highly respected and experienced scientists in the field of caveolins who wrote informative chapters on the role of caveolin-1 in cancer in a format that conveys its role as both a tumor suppressor and tumor promoter. We invite you to read, enjoy and be part of these new promising discoveries that are rapidly advancing the field of cancer research.


Tumor Angiogenesis Wnt signaling growth factor signaling pathways membrane proteins tumor suppression

Editors and affiliations

  • Isabelle Mercier
    • 1
  • Jean-François Jasmin
    • 2
  • Michael P. Lisanti
    • 3
  1. 1.Kimmel Cancer CenterThomas Jefferson UniversityPhiladelphiaUSA
  2. 2.Bluemle Bldg, Rm 939, Department of Stem Cell Biology and RegeThomas Jefferson UniversityPhiladelphiaUSA
  3. 3.Kimmel Cancer CenterThomas Jefferson UniversityPhiladelphiaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Springer, New York, NY
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-1-4614-1000-3
  • Online ISBN 978-1-4614-1001-0
  • Buy this book on publisher's site
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