© 2011

The Nucleolus

  • Mark O. J. Olson

Part of the Protein Reviews book series (PRON, volume 15)

Table of contents

  1. Front Matter
    Pages i-xxv
  2. Nucleolar Structure and Organization

    1. Front Matter
      Pages 1-1
    2. François-Michel Boisvert, Yasmeen Ahmad, Angus I. Lamond
      Pages 29-42
    3. Peter J. Shaw, Peter C. McKeown
      Pages 43-55
    4. Alice Grob, Christine Colleran, Brian McStay
      Pages 83-103
  3. Role of the Nucleolus in Ribosome Biogenesis

    1. Front Matter
      Pages 105-105
    2. Renate Voit, Ingrid Grummt
      Pages 107-134
    3. Franziska Bleichert, Susan Baserga
      Pages 135-156
    4. Marie Gérus, Michèle Caizergues-Ferrer, Yves Henry, Anthony Henras
      Pages 157-184
    5. Rong Cong, Sadhan Das, Philippe Bouvet
      Pages 185-212
    6. Shea Ping Yip, Parco M. Siu, Polly H. M. Leung, Yanxiang Zhao, Benjamin Y. M. Yung
      Pages 213-252
    7. Fang He, Patrick DiMario
      Pages 253-278
  4. Novel Functions of the Nucleolus

    1. Front Matter
      Pages 279-279
    2. Laura A. Tollini, Rebecca A. Frum, Yanping Zhang
      Pages 281-299
    3. David Matthews, Edward Emmott, Julian Hiscox
      Pages 321-345
    4. Andrew Gilder, Michael Hebert
      Pages 361-380

About this book


Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest.  These new discoveries include not only the novel functions of the nucleouls, but also numerous breakthroughs on its conventional role.  Consequently, a large part of this volume is devoted to traditional functions of the nucleolus.  Recent research has led to so much information that the subject cannot be fully contained within one volume, so this book has focused on recent progress in specialized topics within the general subject.

<i>The Nucleolus</i> is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.  Proteomics has shown that there are hundreds of proteins of unknown function in the nucleolus, which are likely to keep researchers busy for years.  In addition, the roles of many viral components in the nucleolus will continue to intrigue us, hopefully moving beyond the phenomenology that is now the case with many viral components in the nucleolus.  Even now, there is already evidence that we can take advantage of our knowledge of the nucleolus to develop therapeutic strategies, and this book hopes to help build the path to a new era of nucleolar translational medical research.

Editors and affiliations

  • Mark O. J. Olson
    • 1
  1. 1.Dept. BiochemistryUniversity of Mississippi Medical CenterJacksonUSA

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