© 2012

Modeling Tumor Vasculature

Molecular, Cellular, and Tissue Level Aspects and Implications

  • Trachette L. Jackson

Table of contents

  1. Front Matter
    Pages i-xi
  2. Cell Signaling and Molecular Aspects of Tumor Blood Vessel Formation

  3. Angiogenesis

    1. Front Matter
      Pages 103-103
    2. Alexander R. A. Anderson, Mark A. J. Chaplain, Stephen McDougall
      Pages 105-133
    3. Yi Jiang, Amy L. Bauer, Trachette L. Jackson
      Pages 135-150
    4. Mark A. J. Chaplain, Steven R. McDougall, Alexander R. A. Anderson
      Pages 167-212
    5. Lance L. Munn, Walid Kamoun, Michael Dupin, James Alex Tyrrell
      Pages 213-233
  4. Whole Organ Modeling of Tumor Growth and Vasculature

    1. Front Matter
      Pages 235-235
    2. Haralambos Hatzikirou, Arnaud Chauvière, John Lowengrub, J. De Groot, Vittorio Cristini
      Pages 237-259
    3. Michael Bergdorf, Florian Milde, Petros Koumoutsakos
      Pages 261-303
    4. Florian Milde, Michael Bergdorf, Petros Koumoutsakos
      Pages 305-334
    5. Michael Welter, Heiko Rieger
      Pages 335-360
    6. Jie Wu, Quan Long, Shi-xiong Xu
      Pages 361-398
  5. Back Matter
    Pages 399-409

About this book


To profoundly understand biology and harness its intricacies for human benefit and the mitigation of human harm requires cross-disciplinary approaches that incorporate sophisticated computational and mathematical modeling techniques. These integrative strategies are essential to achieve rapid and significant progress in issues, in health and disease, which span molecular, cellular and tissue levels. The use of mathematical models to describe various aspects of tumor growth has a very long history, dating back over six decades.  Recently, however, experimental and computational advances have improved our understanding of how processes act at multiple scales to mediate the development of tumor vasculature and drive the advancement of cancer. This book will showcase the development and utilization of new computational and mathematical approaches to address multiscale challenges associated with tumor vascular development.


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Editors and affiliations

  • Trachette L. Jackson
    • 1
  1. 1.Dept. MathematicsUniversity of MichiganAnn ArborUSA

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