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Avian Immunology

  • Albert A. Benedict

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 88)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Lymphoid Development

  3. Lymphocyte Antigens, Receptors, and Factors

    1. Front Matter
      Pages 85-85
    2. John Lifter, Yong Sung Choi
      Pages 99-107
    3. D. G. Gilmour, M. A. Palladino, A. R. Scafuri, L. W. Pollard, A. A. Benedict
      Pages 109-120
  4. Regulation of the Immune Responce

    1. Front Matter
      Pages 135-135
    2. Tolerance

      1. Mary Lofy Rodrick, Constantine H. Tempelis
        Pages 137-145
      2. Edward L. Morgan, Hans A. Abplanalp, Constantine H. Tempelis
        Pages 147-154
    3. Suppressor Cells

      1. R. Michael Blaese, Andrew V. Muchmore, Irma Koski, Nancy J. Dooley
        Pages 155-159
      2. Gerrie A. Leslie, Vali Kermani-Arab
        Pages 175-185
    4. Inherited Immunodeficiency

      1. A. A. Benedict, H. A. Abplanalp, L. W. Pollard, L. Q. Tam
        Pages 197-205
  5. Major Histocompatibility Complex

    1. Front Matter
      Pages 207-207
    2. Structure

      1. W. Elwood Briles, Ruth W. Briles
        Pages 221-225
      2. K. Hála, M. Vilhelmová, J. Hartmanová
        Pages 227-232
    3. Immune Response

      1. A. W. Nordskog, I. Y. Pevzner, C. L. Trowbridge, A. A. Benedict
        Pages 245-256
    4. Cell Interactions

    5. Disease

      1. B. M. Longenecker, F. Pazderka, J. S. Gavora, J. L. Spencer, E. A. Stephens, R. L. Witter et al.
        Pages 287-298
      2. H. A. Stone, W. E. Briles, W. H. McGibbon
        Pages 299-307
      3. Larry D. Bacon, Roy S. Sundick, Noel R. Rose
        Pages 309-318
    6. Inbred Lines

      1. Phillip R. Morrow, Hans Abplanalp
        Pages 319-327
  6. Tumor Immunity

  7. Immunoglobulins

    1. Front Matter
      Pages 363-363
    2. Allotypes

      1. E. K. Wakeland, J. M. Foppoli, A. A. Benedict
        Pages 365-372
      2. James M. Foppoli, Edward K. Wakeland, A. A. Benedict
        Pages 373-380
    3. Binding Sites

  8. Back Matter
    Pages 403-407

About this book

Introduction

The ontogeny of lymphoid cells seems the most appropriate place to start. The early events in T and B cell ontogeny are still confusing. There seems to be no agreement on the data and on the semantics of the question of progenitor vs. stem cells. Nevertheless, we are beginning to understand more about progenitor cells which are committed to particular cell lines, and about stem cells in the sense of having almost unlimited capability of giving rise to undifferentiated progeny. An important future development will be to determine the nature of the substances that attract stem cells and which are produced by specialized thymus epithelium, and perhaps by the bursa. The way stem cells recognize these signals is an important question to answer. Not predictable from mammalian models has been the observation that there is a lack of cells called into the bursa even before the signal for entry of stem cells has been shut off. A likely model suggested that after a certain point in development there were no longer any cells capable of migrating into the bursa and becoming B cells. A fascinating possibility is the suggestion that a cell comes into the bursa, is not committed, then can still wander into the thymus. This cell does not appear to have B cell characteris­ tics; that is, immunoglobulin is not expressed on its surface.

Keywords

T cell antibody antigen genetics histocompatibility immune response immunity immunodeficiency immunoglobulin immunology immunosuppression lymphocytes resistance transplantation vaccine

Editors and affiliations

  • Albert A. Benedict
    • 1
  1. 1.University of Hawaii at ManoaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4613-4169-7
  • Copyright Information Springer-Verlag US 1977
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-4171-0
  • Online ISBN 978-1-4613-4169-7
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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