Biochemistry of Silicon and Related Problems

  • Gerd Bendz
  • Ingvar Lindqvist
  • Vera Runnström-Reio

Part of the Nobel Foundation Symposia book series (NOFS, volume 40)

Table of contents

  1. Front Matter
    Pages i-xi
  2. General Chemistry of Silicon

    1. Front Matter
      Pages 1-1
    2. Ulrich Wannagat
      Pages 77-90
  3. Silicon in Soil, Plants, and Microorganisms

  4. Physiological Significance of Silicon Compounds in Animals and Man

  5. Silicosis and Other Diseases Caused by Silicon Compounds

    1. Front Matter
      Pages 309-309
    2. Irving J. Selikoff
      Pages 311-336
    3. A. G. Heppleston
      Pages 357-379
    4. Milos Chvapil
      Pages 381-392
  6. Biological and Pharmacological Effects of Organo-Silicon Compounds

    1. Front Matter
      Pages 393-393
    2. M. G. Voronkov
      Pages 395-433
    3. Ulrich Wannagat
      Pages 447-472
    4. Robert R. LeVier, Michael L. Chandler, Samuel R. Wendel
      Pages 473-514
  7. Structural and Analytical Aspects of Organosilicon Compounds

    1. Front Matter
      Pages 521-521
    2. Diego Carlström
      Pages 523-534
    3. Jörgen Vessman, Carl-Gustaf Hammar, Björn Lindeke, Signhild Strömberg, Robert LeVier, Ron Robinson et al.
      Pages 535-558
  8. Discussion and Summary

    1. Front Matter
      Pages 559-559
    2. R. J. P. Williams
      Pages 561-576
    3. Gerd Bendz, Ingvar Lindqvist, Vera Runnström-Reio
      Pages 577-586
  9. Back Matter
    Pages 587-591

About this book


Silicon chemistry was initiated in 1823 by Berzelius who prepared elemental silicon. In many ways silicon was considered a typical opposite of carbon, although the two elements are closely related as to their electronic structure, both having four valence electrons. The properties of their compounds are, however, extreme­ ly different. Both form extended structures, but in different ways - carbon by covalent carbon-carbon bonds; silicon by polar silicon- -oxygen-silicon bonds. The complex carbon compounds are integral parts of all living matter, plants and animals. The corresponding silicon compounds build up a major part of dead matter, soils and minerals. As recently as twenty years ago the title of this Symposium, "BiOChemistry of Silicon", would have been considered as contradictio in adjecto. However, the development in the field has, during the past fifteen years, been overwhelming and has convinced us that silicon is a necessary element in the life processes, for animals as well as for plants. Interesting therapeutical uses have been suggested, but we have also become increasingly aware of serious occupational diseases - asbestosis and silicosis - and of possible cancerogenic effects. It is our hope that this volume will give some idea about various aspects of silicon compounds which were discussed during the Symposium.


Calcium animals bacteria biochemistry carbon chemistry development electrons element metabolism mineral pharmacology plants silicon soil

Editors and affiliations

  • Gerd Bendz
    • 1
  • Ingvar Lindqvist
    • 2
  • Vera Runnström-Reio
    • 3
  1. 1.Institute of ChemistryUniversity of UppsalaUppsalaSweden
  2. 2.Department of ChemistrySwedish University of Agricultural SciencesUppsalaSweden
  3. 3.Karolinska InstitutetStockholmSweden

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