Sudden Cardiac Death and Congestive Heart Failure: Diagnosis and Treatment

Proceedings of the Symposium on New Drugs and Devices, held at Philadelphia, PA, October 26 and 27, 1982

  • J. Morganroth
  • E. Neil Moore

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 25)

Table of contents

  1. Front Matter
    Pages I-XV
  2. New Antiarrhythmic Agents: Basic Considerations

    1. E. Neil Moore, Joseph F. Spear
      Pages 1-12
    2. B. F. Hoffman
      Pages 31-38
    3. J. Morganroth, E. Neil Moore
      Pages 39-45
  3. Efficacy Models for Patients with Chronic Ventricular Arrhythmias

  4. Efficacy Models: Acute Ventricular Arrhythmias

  5. Sudden Death: Can it Now be Used as an Endpoint?

  6. New Devices: Pacemakers in the Treatment of Arrhythmias and Prevention of Sudden Cardiac Death

  7. New Cardiac Inotropic Agents

    1. Barrie Levitt
      Pages 256-269
    2. J. Morganroth, E. Neil Moore
      Pages 270-281
  8. Conclusion

    1. Arthur Hull Hayes Jr.
      Pages 282-291
  9. Back Matter
    Pages 292-302

About this book


In Harch of 1980, we organized the first symposium on how to evaluate new antiarrhythmic agents in which the participants included members of the Cardio-Renal Division of the Food and Drug Administration, academic investigators from the United States and Abroad and directors and imple­ mentors of pharmacological research representing the pharmaceutical industry. By bringing together all three elements, it was hoped that better communication and under­ standing would ensue to more rapidly bring new cardiac agents to the American public. This goal was important since a rather limited number of antiarrhythmic agents were and are currently available to treat patients with such disorders in the United States. These agents are needed not only for the treatment of patients with sustained ventricular tachyarrhythmias which produce life-threatening hemodynamic consequences but also and in fact more potentially important as a prophylactic measure in the high risk patient subject to sudden cardiac death. This book represents the proceedings of the third of these Symposiums whose purpose was to evaluate the clinical research methodology and models used in the evaluation of ne" antiarrhythmic agents for not only acute therapeutic inter­ vention but also for the prophylaxis of sudden cardiac death. In addition, new devices have evolved over the past few years that can detect and treat life-threatening cardiac arrhythmias and the evaluation of efficacy and safety of these devices is detailed.


arrhythmia drugs heart heart failure sudden cardiac death

Editors and affiliations

  • J. Morganroth
    • 1
  • E. Neil Moore
    • 2
  1. 1.Likoff Cardiovascular Institute of Hahnemann Medical College and HospitalPhiladelphiaUSA
  2. 2.School of Veterinary MedicineUniversity of PennsylvaniaPhiladelphiaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1983
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-3878-9
  • Online ISBN 978-1-4613-3876-5
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site
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Internal Medicine & Dermatology