Physiology of Membrane Disorders

  • Thomas E. Andreoli
  • Joseph F. Hoffman
  • Darrell D. Fanestil
  • Stanley G. Schultz

Table of contents

  1. Front Matter
    Pages i-xxvii
  2. The Nature of Biological Membranes

    1. Front Matter
      Pages 1-1
    2. J. David Robertson
      Pages 3-24
    3. T. E. Thompson, C. Huang
      Pages 25-44
    4. Guido Guidotti
      Pages 45-55
  3. Methods for Studying Membranes

  4. General Problems in Membrane Biology

    1. Front Matter
      Pages 175-175
    2. James A. Schafer, Thomas E. Andreoli
      Pages 177-190
    3. Philip A. Knauf
      Pages 191-220
    4. Joseph F. Hoffman
      Pages 221-234
    5. Pamela A. Pappone, Michael D. Cahalan
      Pages 249-272
    6. Michael J. Caplan, Steven A. Rosenzweig, James D. Jamieson
      Pages 273-281
    7. Lazaro J. Mandel
      Pages 295-310
    8. Anthony D. C. Macknight, Alexander Leaf
      Pages 311-328
    9. Werner R. Loewenstein
      Pages 329-343
    10. Edward A. Adelberg, Carolyn W. Slayman
      Pages 345-354
    11. Darrell D. Fanestil
      Pages 355-367
    12. Howard C. Rosenberg, Ted H. Chiu Jr., Amir Askari, James W. Putney Jr
      Pages 369-383
  5. Transport Events in Single Cells

    1. Front Matter
      Pages 385-385
    2. Gary Rudnick
      Pages 409-422
    3. Walter F. Boron
      Pages 423-435
    4. Francisco Bezanilla, Michael M. White
      Pages 437-448
    5. Hans Christoph Lüttgau, George Dimitrie Stephenson
      Pages 449-468
    6. Richard W. Tsien, Peter Hess
      Pages 469-490
    7. Richard W. Aldrich, Vincent E. Dionne, Edward Hawrot, Charles F. Stevens
      Pages 491-516
  6. Transport in Epithelia

    1. Front Matter
      Pages 517-517
    2. Stanley G. Schultz
      Pages 519-534
    3. John G. Forte, Terry E. Machen
      Pages 535-558
    4. Don W. Powell
      Pages 559-596
    5. Henrik Westergaard, John M. Dietschy
      Pages 597-608
    6. L. Gabriel Navar, P. Darwin Bell, Andrew P. Evan
      Pages 637-667
    7. Gerhard Giebisch, Peter S. Aronson
      Pages 669-700
    8. Steven C. Hebert, Thomas E. Andreoli
      Pages 701-711
    9. Mark A. Knepper, John L. Stephenson
      Pages 713-726
    10. Linda S. Costanzo, Erich E. Windhager
      Pages 727-750
    11. Michael J. Welsh
      Pages 751-766
  7. Clinical Disorders of Membrane Transport Processes

    1. Front Matter
      Pages 767-767
    2. Alexander Leaf, Anthony D. C. Macknight, Joseph Y. Cheung, Joseph V. Bonventre
      Pages 769-784

About this book


The second edition of Physiology of Membrane Disorders represents an extensive revision and a considerable expansion of the first edition . Yet the purpose ofthe second edition is identical to that of its predecessor, namely, to provide a rational analysis of membrane transport processes in individual membranes, cells, tissues, and organs, which in tum serves as a frame of reference for rationalizing disorders in which derangements of membrane transport processes playa cardinal role in the clinical expression of disease. As in the first edition, this book is divided into a number of individual, but closely related, sections. Part V represents a new section where the problem of transport across epithelia is treated in some detail. Finally, Part VI, which analyzes clinical derangements, has been enlarged appreciably. THE EDITORS xi Preface to the First Edition The purpose of this book is to provide the reader with a rational frame of reference for assessing the pa­ thophysiology of those disorders in which derangements of membrane transport processes are a major factor responsible for the clinical manifestations of disease. In the present context, we use the term "membrane transport to refer to those molecular processes whose cardinal function, broadly speaking, is processes" in a catholic sense, the vectorial transfer of molecules-either individually or as ensembles-across biological interfaces, the latter including those interfaces which separate different intracellular compartments, the cellular and extracellular com­ partments, and secreted fluids-such as glomerular filtrate-and extracellular fluids.


ATPase Biomembran Organe Translation blood cell calcium channels electron microscopy erythrocyte metabolism microscopy pathophysiology physiology plasma membrane skeletal muscle tissue

Editors and affiliations

  • Thomas E. Andreoli
    • 1
  • Joseph F. Hoffman
    • 2
  • Darrell D. Fanestil
    • 3
  • Stanley G. Schultz
    • 1
  1. 1.University of Texas Health Science Center at HoustonHoustonUSA
  2. 2.Yale University School of MedicineNew HavenUSA
  3. 3.University of CaliforniaSan Diego La JollaUSA

Bibliographic information

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