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Model Systems of Development and Aging of the Nervous System

  • Antonia Vernadakis
  • Alain Privat
  • Jean M. Lauder
  • Paola S. Timiras
  • Ezio Giacobini
Book

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Neurons, Neuroglia and Neuronal-Glial Interactions

    1. Front Matter
      Pages 1-1
    2. Kinya Kuriyama, Seitaro Ohkuma
      Pages 43-56
    3. Nicholas W. Seeds, Janet M. Collins, Susan C. Haffke, Dessie Fafoutis
      Pages 101-113
    4. Madeleine Gumpel, François Lachapelle, Michel Baulac, Annick Baron-Van Evercooren, Annie Gansmuller, Claude Jacque et al.
      Pages 115-124
    5. E. Peter Bosch, José G. Assouline, Ramon Lim
      Pages 125-137
    6. Enrico Mugnaini, Paul T. Massa, Sara Szuchet
      Pages 139-170
    7. Alain Prochiantz
      Pages 193-200
    8. Claire Gensburger, Gérard Labourdette, Monique Sensenbrenner
      Pages 209-216
  3. Neuromodulation, Synapse and Receptors

  4. Aging and Regeneration

    1. Front Matter
      Pages 403-403
    2. Ezio Giacobini, Isabella Mussini
      Pages 421-432
    3. Regino Perez-Polo, Karin Werrbach-Perez
      Pages 433-442
    4. Adriana Consolazione, Caterina Aldinio, Lucio Cavicchioli, Alberta Leon, Gino Toffano
      Pages 443-452
    5. Antonia Vernadakis, Nikos Sakellaridis, Dimitra Mangoura, David Davies
      Pages 475-490
  5. Back Matter
    Pages 501-515

About this book

Introduction

The last decade has generated a multitude of studies using in vitro model systems to explore growth and differentiation of the nervous system. Although the findings have been exciting and have revealed unique properties of neural cells, considerable concern continues to be expressed regarding the significance of in vitro findings in terms of their applicability to in vivo biological events. To examine this issue further, a group of scientists pre­ sented and discussed their findings at a conference sponsored by the Institute of Developmental Neuroscience and Aging held in Crete, Greece, 26-29 May 1985. The conference was cosponsored by the University of Crete and was generously supported by the Ministry of Research and Technology of Greece, Tourism Organization of Greece, and also Sandoz and FIDIA. The Directors of the Institute of Developmental Neuroscience and Aging are indebted to these Institutions for their support. For the success of this conference, the Directors owe much to Drs. Eleni Fleischer-Lambropoulos and Yiannis Tsouderos, who spent countless hours in making arrangements so that the participants would have not only a scientific, but also a unique cultural, experience. Several chapters of this book focus on the complex phenomena of neurogenesis and gliogenesis, and the modulation of neuronal differentiation. The concept that neuronal differentiation has both genetic and epigenetic components is documented by elegant studies using both in vitro cultured cells and neurons transplanted in vivo.

Keywords

Nervous System brain dopamine neuromodulation neurons neuroscience neurotransmitter receptor

Editors and affiliations

  • Antonia Vernadakis
    • 1
  • Alain Privat
    • 2
  • Jean M. Lauder
    • 3
  • Paola S. Timiras
    • 4
  • Ezio Giacobini
    • 5
  1. 1.Departments of Psychiatry and PharmacologyUniversity of Colorado School of MedicineDenverUSA
  2. 2.Neurobiologie du DéveloppementINSERM U249Montpellier CedexFrance
  3. 3.Department of AnatomyUniversity of North Carolina School of MedicineChapel HillUSA
  4. 4.Department of Physiology-AnatomyUniversity of CaliforniaBerkeleyUSA
  5. 5.Department of PharmacologySouthern Illinois University School of MedicineSpringfieldUSA

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