© 1987

Human Sleep

Research and Clinical Care


Table of contents

  1. Front Matter
    Pages i-xx
  2. Physiology and Pharmacology of Sleep

    1. Front Matter
      Pages 1-1
    2. Wallace B. Mendelson
      Pages 3-31
    3. Wallace B. Mendelson
      Pages 33-79
    4. Wallace B. Mendelson
      Pages 81-105
    5. Wallace B. Mendelson
      Pages 107-128
    6. Wallace B. Mendelson
      Pages 129-179
  3. Pathology of Sleep

    1. Front Matter
      Pages 181-182
    2. Wallace B. Mendelson
      Pages 183-220
    3. Wallace B. Mendelson
      Pages 221-245
    4. Wallace B. Mendelson
      Pages 247-268
    5. Wallace B. Mendelson
      Pages 269-294
    6. Wallace B. Mendelson
      Pages 295-314
    7. Wallace B. Mendelson
      Pages 315-322
    8. Wallace B. Mendelson
      Pages 323-342
  4. Back Matter
    Pages 343-436

About this book


Sleep plays an important role in the history of the neurosciences. On Easter Monday in 1920, Otto Loewi was awakened in the night by a dream in which he conceived of neurotransmitters communicating across the synapse. He quickly made notes, but in the morning he could not understand his scribbles. The following night, the dream came again. He wrote down his thoughts more carefully and, the next day, conducted the crucial experiment that launched modern neu­ rophysiology (Koelle, 1986). Since the beginning of the modern era of sleep research in the 1950s, we have used the principles of neurotransmission to explore the regulation of sleep. Without resorting excessively to comments on blind men and elephants, however, it is fair to say that the phenomena of sleep and waking can be approached from many perspectives. Among other things, sleep is a process that can be described electri­ cally, an experience that so far defies physiological measurements, and a social behavior. In this book, I have tried to describe the physiology and pharmacology of sleep (Part I) and to relate them to clinical sleep disorders (Part II). Having neither the skill nor the grandiosity of Rous­ seau, I have made no attempt to write an encyclopedia of all that is known on the subject. Rather, I think of this book as more of a snap­ shot, giving a picture of where we are, and it is hoped, a history of how we got here.


adenosine alcoholism central nervous system cognition depression diagnosis electroencephalography (EEG) epidemiology genetics nervous system neuroendocrinology neuroscience perception pharmacology physiology

Authors and affiliations

  1. 1.State University of New York at Stony BrookStony BrookUSA

Bibliographic information

  • Book Title Human Sleep
  • Book Subtitle Research and Clinical Care
  • Editors Wallace Mendelson
  • DOI
  • Copyright Information Springer-Verlag US 1987
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-42627-8
  • Softcover ISBN 978-1-4612-9068-1
  • eBook ISBN 978-1-4613-1921-4
  • Edition Number 1
  • Number of Pages , 456
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Neurology
  • Buy this book on publisher's site
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