© 1988

The Molecular Immunology of Complex Carbohydrates

  • Albert M. Wu
  • L. Garry Adams

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 228)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Antibody Specificity, Epitope and Lectinology

  3. Complex Carbohydrates as Antigens

About this book


During the past three decades, the sugar moiety of complex carbohydrates has been found to be involved in important interactions of immunological specificity of antigens and to participate in a variety of cellular functions. The long polysaccharide side chains of the lipopolysaccharides on the outer membrane of Gram negative organisms provide surface antigens for differential serodiagnosis. Bacterial surface lectins are important in mediating the attachment of bacteria to host cells in the of infectious diseases. The carbohydrate pathogenesis moieties of cell surface glycoconjugates (glycoproteins and glycolipids) of mammals are the sites for intercellular recognition and for the regulatory molecular interactions such as interaction of complex carbohydrate with hormones or hepatic lectins. The carbohydrate side chains of many complex carbohydrates play essential roles as antigenic determinants b of human blood group ABH, Lea, Le , I, and i activities, as the Forssman specific determinant, and as tumor associated antigenic determinants. Prompted by these and other advances in the field, a Symposium on Molecular Immunology of Complex Carbohydrates was organized as a satellite meeting of the 8th International Glycoconjugate Conference held on September 8- 13, 1985, in Houston, Texas, U. S . A. Many eminent scientists contributed their knowledge at this meeting. The lecture and poster materials of the symposium are contained in this proceeding book, which is divided into four Sections and one Appendix. Section I is entitled Antibody Specificity, Epitope, and Lectinology. Dr. Elvin A.


Antigen Colon Oligosaccharid Polysaccharid biochemistry enzymes infectious disease proteins

Editors and affiliations

  • Albert M. Wu
    • 1
  • L. Garry Adams
    • 1
  1. 1.Texas Agricultural Experimental StationTexas A&M UniversityCollege StationUSA

Bibliographic information

  • Book Title The Molecular Immunology of Complex Carbohydrates
  • Authors Albert M. Wu
    L. Garry Adams
  • Series Title Advances in Experimental Medicine and Biology
  • DOI
  • Copyright Information Springer-Verlag US 1988
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-42818-0
  • Softcover ISBN 978-1-4612-8923-4
  • eBook ISBN 978-1-4613-1663-3
  • Series ISSN 0065-2598
  • Edition Number 1
  • Number of Pages XIV, 868
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Immunology
    Biochemistry, general
  • Buy this book on publisher's site
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