Carcinomas of the Head and Neck

Evaluation and Management

  • Charlotte Jacobs

Part of the Cancer Treatment and Research book series (CTAR, volume 52)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Advances in Staging and Primary Treatment

    1. Front Matter
      Pages 1-1
    2. Robert Lufkin, William Hanafee
      Pages 3-30
    3. Randal S. Weber, Scott M. Lippman, Marsha D. McNeese
      Pages 61-81
    4. Patrick L. Welton, Don R. Goffinet, Daniel S. Kapp
      Pages 83-93
    5. Jack L. Gluckman, Robert P. Zitsch
      Pages 95-113
  3. Rehabilitation

    1. Front Matter
      Pages 115-115
    2. Michael D. Trudeau, David E. Schuller
      Pages 117-131
    3. Allen Hillel, Carolynn Patten
      Pages 133-147
  4. Advances in Medical Management and Chemotherapeutic Approaches

    1. Front Matter
      Pages 149-149
    2. Margaret M. Petersen, I. Ross McDougall
      Pages 151-170
    3. Isaiah W. Dimery, Charles D. Wendt, Alan M. Kramer, Robert M. Byers, Waun K. Hong
      Pages 209-222
  5. Basic Biology and Etiology

    1. Front Matter
      Pages 223-223
    2. John F. Ensley, Zosia Maciorowski, Haline Pietraszkiewicz, Filippo deBraud, Wael Sakr
      Pages 225-242
    3. Stimson P. Schantz, Howard E. Savage, Norris K. Lee
      Pages 243-263
  6. Back Matter
    Pages 283-291

About this book


It was not too many years ago that the role of chemotherapy for head and neck cancer consisted of single-agent methotrexate for selected patients with recurrent disease. In the past decade, multiple new agents, high-dose chemotherapy, combinations, and intra-arterial approaches have been used for the patient with recurrent disease. Wheeler critically assesses the current status of these approaches. When oncologists began testing chemotherapy in the combined modality approach, trials consisted of induction chemotherapy and use of single agents as radiosensitizers. Although a great deal has been learned from these trials, benefit in terms of survival has been marginal. Even more promising may be the concomitant use of combination chemo­ therapy and radiation. Taylor describes the encouraging results as well as the potential. Induction chemotherapy may have a second important goal in addition to improving curability-it could be used for organ preservation. Dimery et al., present the background for this approach in the patient with laryngeal cancer as well as a description of their randomized trial for voice preservation. Head and neck squamous cancers are a heterogeneous group of diseases, and surgeons have long sought parameters that will help predict outcome.


Staging Tumor carcinoma computed tomography (CT) diagnosis imaging morbidity rehabilitation ultrasound

Editors and affiliations

  • Charlotte Jacobs
    • 1
  1. 1.Division of Medical Oncology—M211, Department of MedicineStanford University School of MedicineStanfordUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1990
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4612-8806-0
  • Online ISBN 978-1-4613-1499-8
  • Series Print ISSN 0927-3042
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology