© 1990

Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA

  • Stephen J. Peroutka

Part of the Topics in the Neurosciences book series (TNSC, volume 9)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Alexander T. Shulgin
    Pages 1-20
  3. George R. Greer, Requa Tolbert
    Pages 21-35
  4. James B. Bakalar, Lester Grinspoon
    Pages 37-52
  5. Stephen J. Peroutka
    Pages 53-62
  6. James W. Gibb, Donna Stone, Michel Johnson, Glen R. Hanson
    Pages 133-150
  7. Patrica M. Whitaker-Azmitia, Efrain C. Azmitia
    Pages 201-211
  8. Glen R. Hanson, Kalpana M. Merchant, Michel Johnson, Anita A. Letter, Lloyd Bush, James W. Gibb
    Pages 213-224
  9. J. Frank Nash, Herbert Y. Meltzer
    Pages 225-239
  10. Back Matter
    Pages 241-244

About this book


The variety of viewpoints expressed in this book illustrate the many contro­ versies surrounding MDMA [1]. On the one hand, the proponents ofMDMA use believe this agent offers a unique psychoactive effect that may have important clinical applications, especially in the field of psychotherapy. On the other hand, the scientific data concerning the neurotoxic effects of the drug are unequivocal. The most striking feature of the human information of MDMA is the paucity of data that has been generated on the drug since it was patented in 1914. As pointed out by Beck (Chapter 6) and others, a clear need exists for better epidemiological and clinical data on MDMA. In the absence of such data, arguments both for and against the cotinued use ofMDMA with humans will be difficult to support. Unfortunately, the currently available data must be used to develop rational policies for potential human users of MDMA. At the present time, there are no data indicating that recreational doses of MDMA permanently damage the human brain. Nonetheless, based on a review of the contents of this book as well as on informal discussions with approximately 200 recreational users of MDMA, the following personal observations suggest that MDMA is radically different from other recreational drugs.


CNS amphetamine brain clinical application drugs hand health neuropeptides neurotoxicity pharmacology psychotherapy relationships therapy tissue toxicity

Editors and affiliations

  • Stephen J. Peroutka
    • 1
  1. 1.Stanford University Medical CenterUSA

Bibliographic information

  • Book Title Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA
  • Editors Stephen J. Peroutka
  • Series Title Topics in the Neurosciences
  • DOI
  • Copyright Information Springer-Verlag US 1990
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-7923-0305-3
  • Softcover ISBN 978-1-4612-8799-5
  • eBook ISBN 978-1-4613-1485-1
  • Series ISSN 0897-3946
  • Edition Number 1
  • Number of Pages XVI, 244
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Neurology
    Veterinary Medicine/Veterinary Science
  • Buy this book on publisher's site
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