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High Performance Computational Methods for Biological Sequence Analysis

  • Tieng K. Yap
  • Ophir Frieder
  • Robert L. Martino

Table of contents

  1. Front Matter
    Pages i-xix
  2. Tieng K. Yap, Ophir Frieder, Robert L. Martino
    Pages 1-13
  3. Tieng K. Yap, Ophir Frieder, Robert L. Martino
    Pages 15-49
  4. Tieng K. Yap, Ophir Frieder, Robert L. Martino
    Pages 51-97
  5. Tieng K. Yap, Ophir Frieder, Robert L. Martino
    Pages 99-109
  6. Tieng K. Yap, Ophir Frieder, Robert L. Martino
    Pages 111-141
  7. Tieng K. Yap, Ophir Frieder, Robert L. Martino
    Pages 143-157
  8. Tieng K. Yap, Ophir Frieder, Robert L. Martino
    Pages 159-189
  9. Tieng K. Yap, Ophir Frieder, Robert L. Martino
    Pages 191-193
  10. Back Matter
    Pages 195-211

About this book

Introduction

High Performance Computational Methods for Biological Sequence Analysis presents biological sequence analysis using an interdisciplinary approach that integrates biological, mathematical and computational concepts. These concepts are presented so that computer scientists and biomedical scientists can obtain the necessary background for developing better algorithms and applying parallel computational methods. This book will enable both groups to develop the depth of knowledge needed to work in this interdisciplinary field.
This work focuses on high performance computational approaches that are used to perform computationally intensive biological sequence analysis tasks: pairwise sequence comparison, multiple sequence alignment, and sequence similarity searching in large databases. These computational methods are becoming increasingly important to the molecular biology community allowing researchers to explore the increasingly large amounts of sequence data generated by the Human Genome Project and other related biological projects. The approaches presented by the authors are state-of-the-art and show how to reduce analysis times significantly, sometimes from days to minutes.
High Performance Computational Methods for Biological Sequence Analysis is tremendously important to biomedical science students and researchers who are interested in applying sequence analyses to their studies, and to computational science students and researchers who are interested in applying new computational approaches to biological sequence analyses.

Keywords

algorithms biology databases genome molecular biology processor sequence analysis

Authors and affiliations

  • Tieng K. Yap
    • 1
  • Ophir Frieder
    • 2
  • Robert L. Martino
    • 1
  1. 1.National Institutes of HealthBethesdaUSA
  2. 2.George Mason UniversityFairfaxUSA

Bibliographic information

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