© 1994

Callosal Agenesis

A Natural Split Brain?

  • Maryse Lassonde
  • Malcolm A. Jeeves

Part of the Advances in Behavioral Biology book series (ABBI, volume 42)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Neuroclinical Findings

    1. Clinical Description and Related Disorders

      1. Krystyna E. Wisniewski, Joseph S. Jeret
        Pages 1-6
      2. Jean Aicardi, Jean-Jacques Chevrie
        Pages 7-17
      3. Stirling Carpenter
        Pages 27-30
      4. Eva Andermann, Frederick Andermann, Richard Nagy, Denis Bergeron, Jean Mathieu, Pierre Langevin
        Pages 31-38
    2. Neurorndiological Characteristics

      1. Patrizia Vergani, Nicola Strobelt
        Pages 63-67
      2. Giovanni Cioni, Laura Bartalena, Enrico Biagioni, Antonio Boldrini
        Pages 69-76
      3. Denis Melanson, Armando Salazar, Raquel del Carpio-O’Donovan
        Pages 77-82
      4. Ronald A. Rauch, J. Randy Jinkins
        Pages 83-95
    3. Neurorndiological Characteristics

      1. Tore A. Nielsen, Jacques Montplaisir, Roger Marcotte, Maryse Lassonde
        Pages 109-117
  3. Animal Models

    1. Douglas Wahlsten, Hiroki S. Ozaki
      Pages 125-133
    2. Jaime Olavarria, Marcos M. Serra-Oller, Kathleen T. Yee, Richard C. Van Sluyters
      Pages 135-146
  4. Neuropsychological Description

    1. Sensory and Sensorimotor Functions

      1. Franco Lepore, Maryse Lassonde, Pierre Poirier, Alessandra Schiavetto, Nathalie Veillette
        Pages 155-169
      2. A. David Milner
        Pages 171-183

About this book


This book is devoted to the description of agenesis of the corpus callosum, a congenital malformation of midline structures in the brain that may be regarded as a natural model of the "split-brain. " First reported by Rei! in 1812, this anomaly has since been described by several investigators. Interest in this malformation was revived in the 1970s by studies of interhemispheric transfer in Bogen and Vogel's commissurotomized patients and the subsequent findings by Sperry that acallosal patients were devoid of the typical disconnection deficits found in patients with surgical transection of the corpus callosum. Since this seminal work, the bulk of neuropsychological research on callosal agenesis has focused on the particulars of interhemispheric transfer and integration. An ever-growing literature has emerged on the subject, attempting to specify the extent and limits of neural plasticity in a nervous system that has evolved in the absence of the most important interhemispheric pathway. Whilst callosal agenesis proves to be an excellent model of cerebral plasticity, it has to be pointed out that this anomaly is often associated with other malformations and neurological diseases that may result in different degrees of mental retardation or other cognitive and sensorimotor deficits. In this context, neurological research on callosal agenesis has concentrated on the description of various syndromes associated with this pathology as well as on the attempt to specify its neurobehavioral manifestations.


Nervous System Syndrom brain electroencephalography (EEG) forebrain syndromes

Editors and affiliations

  • Maryse Lassonde
    • 1
  • Malcolm A. Jeeves
    • 2
  1. 1.Université de MontréalMontréalCanada
  2. 2.University of St. AndrewsSt. AndrewsScotland, UK

Bibliographic information

  • Book Title Callosal Agenesis
  • Book Subtitle A Natural Split Brain?
  • Editors Maryse Lassone
    Malcolm A. Jeeves
  • Series Title Advances in Behavioral Biology
  • DOI
  • Copyright Information Springer-Verlag US 1994
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-44660-3
  • Softcover ISBN 978-1-4612-7592-3
  • eBook ISBN 978-1-4613-0487-6
  • Series ISSN 0099-6246
  • Edition Number 1
  • Number of Pages , 318
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Neurology
  • Buy this book on publisher's site
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