© 2001

ART and the Human Blastocyst

  • David K. Gardner
  • Michelle Lane
Conference proceedings

Part of the Proceedings in the Serono Symposia USA Series book series (SERONOSYMP)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Gamete Quality and Pregnancy Outcome

    1. Front Matter
      Pages 1-1
    2. John A. Schnorr, Howard W. Jones Jr.
      Pages 3-20
    3. David R. Meldrum
      Pages 21-28
    4. Denny Sakkas, Odette Moffatt, Mathew Tomlinson, GianCarlo Manicardi, Davide Bizzaro
      Pages 38-48
  3. Physiology of the Embryo

    1. Front Matter
      Pages 49-49
    2. Henry J. Leese, Franchesca D. Houghton, Donald A. Macmillan, Isabelle Donnay
      Pages 61-68
    3. Michelle Lane, David K. Gardner
      Pages 69-90
    4. Tom P. Fleming, M. Reza Ghassemifar, Judith Eckert, Aspasia Destouni, Bhavwanti Sheth, Fay Thomas et al.
      Pages 91-102
  4. Blastocyst Development in Culture

    1. Front Matter
      Pages 103-103
    2. David K. Gardner, Michelle Lane, William B. Schoolcraft
      Pages 118-143
    3. Kate Hardy, Sophie Spanos
      Pages 144-154
    4. Natalie A. Cekleniak, Katharine V. Jackson, Catherine Racowsky
      Pages 155-163
  5. Blastocyst Transfer and Fate

    1. Front Matter
      Pages 165-165
    2. William B. Schoolcraft
      Pages 184-187
    3. Yves Menezo, Denny Sakkas, Anna Veiga
      Pages 188-195

About these proceedings


The field of human artificial reproductive technology (ART) is continually advancing and has witnessed significant changes since the inception of Louise Brown in 1978. Though Louise Brown herself was conceived after the trans­ fer of a blastocyst, there remain significant confusion and debate regarding the stage at which the human embryo conceived in the laboratory should be replaced in the mother. Developments in culture media formulations, leading to the introduction of sequential media, have brought the role of the blasto­ cyst in human ART back into the spotlight. It was due to this resurgence of interest in the niche of extended culture in human infertility treatment that the symposium on "ART and the Human Blastocyst" was held. of this meeting within this volume bring to the forefront The proceedings the main issues raised with the transfer of embryos at the blastocyst stage. It is evident from the chapters that follow that ART needs to be perceived as a continuum of procedures, each one dependent on the preceding one, and all equally as important as each other. That is to say, the development of a com­ petent embryo is ultimately dependent on the quality of the gametes from which it was derived. With regard to the oocyte, this then places the emphasis on the physician to use a stimulation protocol that both produces quality oocytes and does not impair endometrial function. Maintenance of gamete and embryo quality is the laboratory's role.


Embryo development homeostasis hormone metabolism pregnancy

Editors and affiliations

  • David K. Gardner
    • 1
  • Michelle Lane
    • 1
  1. 1.Colorado Center for Reproductive MedicineEnglewoodUSA

Bibliographic information

  • Book Title ART and the Human Blastocyst
  • Editors David K. Gardner
    Michelle Lane
  • Series Title Proceedings in the Serono Symposia USA Series
  • DOI
  • Copyright Information Springer-Verlag New York, Inc. 2001
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-387-95245-1
  • Softcover ISBN 978-1-4612-6540-5
  • eBook ISBN 978-1-4613-0149-3
  • Edition Number 1
  • Number of Pages XVI, 254
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Endocrinology
  • Buy this book on publisher's site
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