© 1985

International Symposium: Retroviruses and Human Pathology

  • Robert C. Gallo
  • Dominique Stehelin
  • Oliviero E. Varnier

Part of the Experimental Biology and Medicine book series (EBAM, volume 11)

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Introduction: The Role of Retroviruses

    1. Front Matter
      Pages xxiii-xxiii
    2. Carmine A. Romanzi
      Pages 1-1
    3. N. Oker-Blom, S. Pfeifer-Ohlsson, K. Alitalo
      Pages 3-17
    4. R. Dulbecco
      Pages 19-33
  3. W. P. Rowe Memorial Lecture

    1. Front Matter
      Pages 34-34
    2. J. A. Levy
      Pages 35-59
  4. Retroviruses and the Murine Model System

  5. Retroviruses and the Vertebrate Model System

    1. Front Matter
      Pages 151-151
    2. S. Rasheed
      Pages 153-175

About this book


For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line· of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological expertise that opened a new approach to the search for a human retrovirus. The rewards came with the discovery that the genes responsible for neoplastic transformation (oncogenes) are of cellular origin and can be shuttled about by retroviruses, and with the identification of a new family of Human T-cell Lymphotrophic retroViruses (HTLV) from patients with diseases ranging from leukemia to the acquired immunodeficiency syndrome (AIDS). An understanding of the role and significance of retroviruses in human pathology requires basic knowledge of the major animal systems studied. With this perspective in mind, we present here a survey that includes general overviews, minireviews on each animal system studied with selected experimental reports and, finally, a stimulating review of the field of human retrovirology by many of the pioneer scientists who created it. We are especially grateful to Profs. C. A. Romanzi and G. C. Schito for promoting the organization of the Symposium. On behalf of the Sym­ posium Committee, we thank E. Soeri, L. Casarino, G. P. Gesu, M.


AIDS Antigen diseases histocompatibility immunodeficiency infection infections leukemia molecular biology pathology proteins psoriasis retroviruses virology virus

Editors and affiliations

  • Robert C. Gallo
    • 1
  • Dominique Stehelin
    • 2
  • Oliviero E. Varnier
    • 3
  1. 1.National Institutes of HealthBethesdaUSA
  2. 2.Institut PasteurLilleFrance
  3. 3.Istituto di MicrobiologiaUniversity of GenovaGenovaItalia

Bibliographic information

  • Book Title International Symposium: Retroviruses and Human Pathology
  • Authors Robert C. Gallo
    Dominique Stehelin
    Oliviero E. Varnier
  • Series Title Experimental Biology and Medicine
  • DOI
  • Copyright Information Humana Press 1985
  • Publisher Name Humana Press
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-89603-098-5
  • Softcover ISBN 978-1-4612-9396-5
  • eBook ISBN 978-1-4612-5008-1
  • Edition Number 1
  • Number of Pages XXIV, 557
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Immunology
  • Buy this book on publisher's site
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