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Purines in Cellular Signaling

Targets for New Drugs

  • Conference proceedings
  • © 1990

Overview

Editors:
  1. Kenneth A. Jacobson

    1. Laboratory of Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, USA

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  2. John W. Daly

    1. Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Vincent Manganiello

    1. Laboratory of Cellular Metabolism, National Heart, Lung, and Blood Institute, NIH, Bethesda, USA

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (54 papers)

  1. Adenosine Receptors and Effector Systems

    1. Adenosine is an Antiinflammatory Autocoid: Adenosine Receptor Occupancy Promotes Neutrophil Chemotaxis and Inhibits Superoxide Anion Generation

      • B. N. Cronstein, L. Angaw-Duguma, D. Nicholls, A. Hutchison, M. Williams
      Pages 114-119

    2. Beta Adrenergic Receptor Mediated Stimulation of Adenine Nucleotide Catabolism and Purine Release in Human Adipocytes

      • H. Kather
      Pages 120-125

    3. Structure Activity Relationships for Adenosine Antagonists

      • R. F. Bruns
      Pages 126-135

    4. Structure Activity Relationships for Adenosine Agonists

      • B. K. Trivedi
      Pages 136-145

    5. The Design of a Series of Highly A2 Selective Adenosine Agonists

      • A. J. Hutchison, H. Oei, M. Jarvis, M. Williams, R. L. Webb
      Pages 146-151

    6. Adenosine Agonists. Characterization of the N6-Subregion of the Adenosine A2 Receptor via Molecular Modeling Techniques

      • D. F. Ortwine, A. J. Bridges, C. Humblet, B. K. Trivedi
      Pages 152-157

    7. Physiological and Biochemical Aspects of “P”-Site-Mediated Inhibition of Adenylyl Cyclase

      • R. A. Johnson, S.-M. H. Yeung, M. Bushfield, D. Stübner, I. Shoshani
      Pages 158-165

    8. Adenosine Receptors Mediating Inhibition of Peripheral and Central Neurons

      • J. A. Ribeiro, A. M. Sebastiao
      Pages 166-173

    9. Adenosine Receptors as Drug Targets: Fulfilling the Promise?

      • M. Williams
      Pages 174-183

    10. Mechanisms of Adenosine Action

      • B. B. Fredholm, J. Fastbom, M. Dunér-Engström, P.-S. Hu, I. van der Ploeg, N. Altiok et al.
      Pages 184-193

    11. Functional Roles of A1 and A2 Receptors in Rat Hippocampus and Striatum

      • T. V. Dunwiddie, C. R. Lupica, W. A. Cass, N. R. Zahniser, M. Williams
      Pages 194-199

    12. Subclassification of Neuronal Adenosine Receptors

      • L. E. Gustafsson, C. U. Wiklund, N. P. Wiklund, L. Stelius
      Pages 200-205

    13. Effects of Adenosine on Mast Cells

      • M. J. Lohse, K.-N. Klotz, K. Maurer, I. Ott, U. Schwabe
      Pages 206-212

    14. The Role of Adenosine on the Gastric Acid Secretory Response

      • J. G. Gerber, N. A. Payne
      Pages 213-219

    15. Adenosine Receptors and Signaling in the Kidney

      • W. S. Spielman, L. J. Arend, K.-N. Klotz, U. Schwabe
      Pages 220-225

    16. Inhibition of the Function of Guanine Nucleotide Binding Proteins by the New Positive Inotropes

      • V. Ramkumar, G. L. Stiles
      Pages 226-233

    17. Blockade of Antigen Activated Signals by Xanthine Analogs in RBL-2H3 Cells: Evidence for a Novel Adenosine Receptor

      • H. Ali, D. Collado-Escobar, D. O’Reilly, M. Beaven
      Pages 233-238

  2. Adenine Nucleotide Receptors and Effector Systems

    1. Front Matter

      Pages 239-239
      Download chapter PDF

    2. Classification and Characterization of Purinoceptors

      • G. Burnstock
      Pages 241-253

    3. Structure Activity Relationships for Adenine Nucleotide Receptors on Mast Cells, Human Platelets, and Smooth Muscle

      • N. J. Cusack, S. M. O. Hourani
      Pages 254-259
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Keywords

Editors and Affiliations

  • Laboratory of Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, USA

    Kenneth A. Jacobson

  • Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, USA

    John W. Daly

  • Laboratory of Cellular Metabolism, National Heart, Lung, and Blood Institute, NIH, Bethesda, USA

    Vincent Manganiello

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