© 2004

Bone Formation

  • Summarizes new knowledge of the many steps that lead to the formation of bone

  • Contributors are international experts in their field

  • Contains a chapter on biomechanics – a topic rarely included in books, that emphasizes molecular and cellular aspects


Part of the Topics in Bone Biology book series (TBB, volume 1)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Prasanna Bukka, Marc D. McKee, Andrew C. Karaplis
    Pages 1-17
  3. Norman J. Karin, Mary C. Farach-Carson
    Pages 18-43
  4. Marja M. Hurley, Joseph A. Lorenzo
    Pages 44-70
  5. Charles H. Turner
    Pages 79-105
  6. T. John Martin, Ego Seeman
    Pages 106-119
  7. William McLean, Bjorn R. Olsen
    Pages 120-137
  8. Back Matter
    Pages 155-160

About this book


Bone research in recent years has generated much new knowledge, in large measure because of the broad public health implications of osteoporosis and related bone disorders. Bone Formation, the first in a series entitled Topics in Bone Biology, evaluates this new information and formulates novel insights and hypotheses within the broad framework of current knowledge. An easy-to handle and to read work, with concise reviews that are extensively referenced, the chapters in this book are written by internationally known authorities. Particular emphasis is on osteoporosis and related disorders of diminished bone formation. Among the general topics treated is a chapter on biomechanical aspects of bone formation, not often considered in relation to diseases of bone formation. The book constitutes essential reading for those entering the field of bone biology and those who wish to become familiar with up-to-date information in a particular area of bone research.


Calcium Farach-Carson Pathogene Public Health biology biomechanics bone metabolism osteoporosis prevention

Authors and affiliations

  1. 1.Department of BioStructure and Function, Department of PharmacologyUniversity of Connecticut Health CenterFarmingtonUSA
  2. 2.Department of Biological SciencesUniversity of DelawareNewarkUSA

Bibliographic information

Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


From the reviews of the first edition:

"Bone Formation … focuses on the cells that initiate the process of osteogenesis, its regulation, and its disorders. … Experimentalists will appreciate the large amount of cell culture and cell line information made available in the form of extensive tables not readily available elsewhere. … This fundamental science book gives a clear view of the most recent knowledge in research on bone formation. It is presented in a way that makes it easily accessible to an orthopedic surgeon … ." (Claude Karger, European Journal of Orthopaedic Surgery & Traumatology, Vol. 14 (4), 2004)