Bone Metastases

Diagnosis and Treatment

  • R. D. Rubens
  • I. Fogelman

Table of contents

  1. Front Matter
    Pages i-xii
  2. R. D. Rubens
    Pages 1-10
  3. I. Fogelman, J. H. McKillop
    Pages 31-61
  4. Sheila Rankin
    Pages 63-81
  5. M. A. Richards
    Pages 83-97
  6. R. E. Coleman
    Pages 99-120
  7. D. J. Dodwell, A. Howell
    Pages 121-147
  8. Susan E. M. Clarke
    Pages 187-205
  9. C. Terrell, J. R. Wedley
    Pages 223-241
  10. Back Matter
    Pages 243-247

About this book


Bone Metastases brings together the many recent developments that are gradually improving the prospects for patients with secondary involvement of the skeleton in a primary cancer elsewhere. The morbidity from bone metastases is extensive, and the palliative and supportive treatment that sufferers require for many months or even years constitutes a major health problem. A multidisciplinary approach is essential since a variety of specialists are involved: radiation and medical oncologists, general and orthopaedic surgeons, general physicians, radiologists and nuclear medicine physicians, symptom control and terminal care specialists. The book's editors, themselves authorities in the fields of oncology and bone disease respectively, have brought together experts from all these disciplines to provide comprehensive coverage of metastatic bone disease. They cover the biology and pathophysiology, hypercalcaemia, imaging, assessment of response to treatment, types of treatment (systemic, radiotherapy, surgery), and symptomatic and supportive care. Particularly new approaches included are magnetic resonance imaging, the assessment of skeletal response and isotope therapy.


bone cancer computed tomography (CT) imaging magnetic resonance magnetic resonance imaging magnetic resonance imaging (MRI) metastasis metastatic disease morbidity pathogenesis pathophysiology radiation radiology radiotherapy

Editors and affiliations

  • R. D. Rubens
    • 1
  • I. Fogelman
    • 2
  1. 1.Imperial Cancer Research Fund Clinical Oncology UnitUnited Medical and Dental Schools of Guy’s and St Thomas’s Hospitals, Guy’s HospitalLondonUK
  2. 2.Department of Nuclear MedicineGuy’s HospitalLondonUK

Bibliographic information

Industry Sectors
Health & Hospitals
Oncology & Hematology