Progressive Multiple Sclerosis

  • Alastair¬†Wilkins

Table of contents

  1. Front Matter
    Pages i-xii
  2. Alastair Wilkins
    Pages 1-9
  3. Stanley Hawkins, Alastair Wilkins
    Pages 11-30
  4. Neil Robertson, Claire Hirst
    Pages 31-50
  5. Lars Bo, Nikos Evangelou, Emma Tallantyre
    Pages 51-70
  6. Alastair Wilkins
    Pages 71-92
  7. Declan Chard, David Miller
    Pages 93-114
  8. Axel Petzold
    Pages 115-146
  9. Claire M. Rice, Alastair Wilkins
    Pages 147-186
  10. Back Matter
    Pages 245-251

About this book


Progressive multiple sclerosis places a huge burden on individuals, carers and society and treatment options are currently limited. However, there have been significant recent advances in understanding progressive disease and this book draws the field together into a single, accessible, clinically focused text.

Progressive Multiple Sclerosis sets out the basic science, pathology, epidemiology and treatment possibilities in progressive multiple sclerosis. The biological processes underlying disease progression are elucidated as are specific pathophysiological mechanisms. The basic science of axonal degeneration and the clinical understanding of progressive multiple sclerosis are discussed in the context of emerging and future therapies for disease progression as are trials which might be conducted for progressive multiple sclerosis. An overview of biomarkers for the disease is included and existing symptomatic therapies for progressive multiple sclerosis are covered in detail. Each chapter addresses specific aspects of progressive multiple sclerosis providing an extensive review of the current literature and a discussion of the likely mechanisms of tissue injury relevant to the disease.

Progressive Multiple Sclerosis is ideal for both general neurologists and those with a specialist interest in multiple sclerosis. It will also be of interest to neurologists in training and other medical professionals treating this common disease.

Dr Alastair Wilkins is Senior Lecturer in Neurology, University of Bristol, and Consultant Neurologist at Frenchay Hospital, Bristol, UK. He researches axonal injury in multiple sclerosis and related disorders.


Biomarkers Diagnosis Epidemiology Multiple Sclerosis Pathophysiology Progressive Therapy

Editors and affiliations

  • Alastair¬†Wilkins
    • 1
  1. 1., Department of NeurologyFrenchay HospitalBristolUnited Kingdom

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag London 2013
  • Publisher Name Springer, London
  • eBook Packages Medicine
  • Print ISBN 978-1-4471-2394-1
  • Online ISBN 978-1-4471-2395-8
  • Buy this book on publisher's site
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