Prostatic Obstruction

Pathogenesis and Treatment

  • Christopher R. Chapple

Table of contents

  1. Front Matter
    Pages i-xx
  2. The Importance of Neural Factors in the Presentation and Treatment of Prostatic Obstruction

    1. Front Matter
      Pages 1-1
    2. C. R. Chapple
      Pages 3-11
    3. C. R. Chapple
      Pages 13-23
    4. C. R. Chapple
      Pages 25-41
  3. Contemporary Management of Bladder Outflow Obstruction

    1. Front Matter
      Pages 77-77
    2. R. Turner-Warwick
      Pages 79-102
    3. J. G. Noble, C. R. Chapple
      Pages 103-112
    4. J. W. H. Evans, N. MacCartney
      Pages 113-145
    5. E. J. G. Milroy
      Pages 147-163
    6. T. J. Christmas
      Pages 165-173
    7. J. Brantley Thrasher, K. J. Kreder
      Pages 175-188
    8. J. G. Noble
      Pages 213-228
  4. Back Matter
    Pages 229-234

About this book


The human prostate gland is of undoubted importance in reproductive physiology and is one of the commonest causes of clinical urological problems in the male patient. Despite the wealth of published lit­ erature relating to the prostate gland surprisingly little is understood about its neural innervation, the influence of pharmacological factors and its precise physiological functions. Indeed, benign disorders of the prostate gland including benign prostatic hyperplasia, bladder neck dyssynergia and inflammatory disorders of the prostate (prostatitis, prostatodynia) although well recognised clinically, are as yet poorly characterised and understood. It was not until the late 1960s that the subject of urodynamics, which for the first time allowed scientific assessment of the function of the lower urinary tract, was introduced. The first section of this book considers recent advances in our understanding of the innervation of the bladder and prostate gland and the changes in bladder function which accompany prostate medi­ ated bladder outflow obstruction. The clinical consequence of benign prostatic hyperplasia in many patients is bladder outflow obstruction and although the traditional treatment of these conditions is by the use of ablative surgery, in recent years a number of new modalities have been investigated and are reviewed in the second section of the book.


Benign Prostatic Hyperplasia Physiology of Bladder and Prostate Treatment endoscopy muscle pharmacology physiology prostate prostatectomy respiratory system surgery ultrasound

Authors and affiliations

  • Christopher R. Chapple
    • 1
  1. 1.The Central Sheffield University HospitalsRoyal Hallamshire HospitalSheffieldUK

Bibliographic information

Industry Sectors
Health & Hospitals