Multiple Sclerosis

Advances in Clinical Trial Design, Treatment and Future Perspectives

  • Donald E. Goodkin
  • Richard A. Rudick

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Jorge R. Oksenberg, Stephen L. Hauser
    Pages 17-46
  3. Brian G. Weinshenker
    Pages 105-122
  4. Nicholas G. LaRocca, Paul G. Ritvo, Deborah M. Miller, Jill S. Fischer, Howard Andrews, Donald W. Paty
    Pages 145-160
  5. Richard A. Rudick, William Sibley, Luca Durelli
    Pages 223-250
  6. Donald E. Goodkin, Jill S. Fischer
    Pages 251-287
  7. Kenneth P. Johnson, M. B. Bornstein
    Pages 289-312
  8. Jack C. Sipe, J. S. Romine, J. Zyroff, J. Koziol, E. Beutler
    Pages 313-334
  9. Back Matter
    Pages 361-364

About this book


Multiple Sclerosis: Advances in Clinical Trial Design, Treatment and Future Perspectives is a review of therapeutic developments for a disease that is one of the major problems in current neurologic practice. Progress in this field has been rapid and there have been important developments in clinical trial design and a number of important trial results that have resulted in new treatment options for patients and physicians. Important ethical considerations that arise with new treatments are included, as is a perspective on the emergence of MS as a treatable disease. This book is for all neurologists, primary care physicians, and patients concerned about the treatment of MS. It will also be of value to clinical epidemiologists and biostatisticians with an interest in experimental therapies for chronic disease, to immunologists with an interest in autoimmune disease, to the pharmaceutical industry and to MS societies.


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Editors and affiliations

  • Donald E. Goodkin
    • 1
  • Richard A. Rudick
    • 2
  1. 1.The UCSF/Mount Zion Multiple Sclerosis CenterUniversity of California at San FranciscoSan FranciscoUSA
  2. 2.Mellen Center for Multiple Sclerosis Treatment and ResearchCleveland Clinic FoundationClevelandUSA

Bibliographic information

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