© 2012

Innate Immune Regulation and Cancer Immunotherapy

  • Rongfu Wang

Table of contents

  1. Front Matter
    Pages i-x
  2. Rong-Fu Wang
    Pages 1-5
  3. Jessica J. O’Konek, Masaki Terabe, Jay A. Berzofsky
    Pages 7-21
  4. Lawrence S. Lamb Jr.
    Pages 23-38
  5. Shin-Ichiroh Saitoh
    Pages 39-49
  6. Helen Y. Wang, Rong-Fu Wang
    Pages 61-88
  7. Meredith O’Keeffe, Mireille H. Lahoud, Irina Caminschi, Li Wu
    Pages 89-119
  8. Gregory Lizée, Michel Gilliet
    Pages 121-145
  9. Tyler J. Curiel
    Pages 147-173
  10. Ilona Kryczek, Ke Wu, Ende Zhao, Guobin Wang, Weiping Zou
    Pages 175-193
  11. Bin Li, Rong-Fu Wang
    Pages 195-216
  12. Wiaam Badn, Vincenzo Bronte
    Pages 217-229
  13. Ge Ma, Ping-Ying Pan, Shu-Hsia Chen
    Pages 231-250
  14. Caroline Murphy, Luke A. J. O’Neill
    Pages 267-287
  15. Joanne E. Konkel, WanJun Chen
    Pages 289-301
  16. Ryo Ueda, Tomonori Yaguchi, Yutaka Kawakami
    Pages 335-345

About this book


There has been major growth in understanding innate immune signaling, inflammation, immune suppression and cancer immunotherapy. Innate immune regulation and cancer immunotherapy highlights emerging research about the underlying mechanisms of innate immunity and signaling regulation, inflammation and immune suppression that promote or inhibit cancer development and progression, and offers novel ideas and strategies to develop therapeutic cancer drugs or cell therapy by manipulating or blocking these negative signaling pathways and generating potent antitumor immunity.  Recent studies have identified key innate immune receptors or sensors, novel signaling molecules and immune regulatory molecules that control immune responses, inflammation and immune suppression in cancer and other diseases. Major progresses in understanding of tumor antigens, immune suppressive molecules and cell population and novel vaccine strategies bring therapeutic cancer vaccines and drugs in realty.  With chapters written by internationally recognized contributors, this book provides essential introduction and guide for immunologists, basic, translational and clinical cancer researchers.

Features of this book:

Offers the most recent development from basic science to clinical application of cancer immunotherapy, thus serving useful guide for immunologists, and cancer researcher and oncologists.

Identify key immune signaling molecules and cell populations that dampen immune responses against cancer, thus providing novel strategies to develop therapeutic cancer vaccines and drugs.


Myeloid-Derived Suppressive Cells NKT Cells Toll-Like Receptors regulatory T cells γδ T Cells

Editors and affiliations

  • Rongfu Wang
    • 1
  1. 1.Center for Cell & Gene TherapyBaylor College of MedicineHoustonUSA

Bibliographic information

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