Metal Ion in Stroke

  • Yang V. Li
  • John H. Zhang

Part of the Springer Series in Translational Stroke Research book series (SSTSR)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Yang V. Li, John H. Zhang
    Pages 1-12
  3. Calcium (Ca)

    1. Front Matter
      Pages 13-13
    2. Jillian C. Belrose, Fabiana A. Caetano, Kai Yang, Brian M. W. Lockhart, Michael F. Jackson, John F. MacDonald
      Pages 15-39
    3. Maria Josè Sisalli, Claudia Savoia, Antonella Scorziello
      Pages 41-67
    4. Anna Poggesi, Domenico Inzitari
      Pages 69-101
    5. Elena Alberdi, María Domercq, Carlos Matute
      Pages 103-127
  4. Zinc (Zn)

    1. Front Matter
      Pages 165-165
    2. Yang V. Li
      Pages 167-189
    3. Richard B. Thompson
      Pages 209-226
    4. Robert A. Colvin, Christian J. Stork, Yang V. Li, Barry Lai
      Pages 227-237
  5. Iron (Fe)

    1. Front Matter
      Pages 239-239
    2. Chih Ming Lin, Magdy Selim
      Pages 241-253
    3. Dimitrios Galaris, Natalia Kitsati, Sygkliti-Henrietta Pelidou, Alexandra Barbouti
      Pages 255-271
    4. Jin-Yul Lee, Richard F. Keep, Ya Hua, Aditya Pandey, Guohua Xi
      Pages 273-282
    5. Mónica Millán, Natalia Pérez de la Ossa, Teresa Gasull
      Pages 283-301
  6. Sodium (Na)

    1. Front Matter
      Pages 303-303
    2. Mauro Cataldi, Pasquale Molinaro, Lucio Annunziato
      Pages 305-331
    3. Victor E. Yushmanov, Alexander Kharlamov, Fernando E. Boada, Stephen C. Jones
      Pages 333-359
  7. Potassium (K)

    1. Front Matter
      Pages 361-361
    2. Piotr Bednarczyk
      Pages 373-389
    3. David R. Harder, Maia Terashvili, Debebe Gebremedhin
      Pages 391-408
  8. Magnesium (Mg)

    1. Front Matter
      Pages 429-429
    2. Renée J. Turner, Frances Corrigan, Robert Vink
      Pages 445-460
    3. Bruno P. Meloni, Kym Campbell, Neville W. Knuckey
      Pages 461-480
    4. Peter Yat-Ming Woo, George Kwok-Chu Wong, Matthew Tak-Vai Chan, Wai Sang Poon
      Pages 481-521
  9. Selenium (Se)

    1. Front Matter
      Pages 523-523
    2. Nic E. Savaskan, Nirjhar Hore, Ilker Y. Eyupoglu
      Pages 525-536
  10. Manganese (Mn)

    1. Front Matter
      Pages 547-547
    2. Steven C. Fordahl, Keith M. Erikson
      Pages 549-567
    3. Thomas E. Gunter, Claire E. Gavin, Karlene K. Gunter
      Pages 591-606
  11. Copper (Cu)

    1. Front Matter
      Pages 607-607
    2. Ya Hui Hung, Ashley I. Bush, Robert A. Cherny
      Pages 609-645
  12. Exogenous Metal Ions: Aluminum (Al), Arsenic (As), Cadmium (Cd), Mercury (Hg), and Nickel (Ni)

    1. Front Matter
      Pages 647-647
    2. Chih-Hao Wang, Chien-Jen Chen
      Pages 681-702
    3. Haris Carageorgiou, Myrto Katramadou
      Pages 703-749
    4. Rodrigo Bainy Leal, Débora Kurrle Rieger, Tanara Vieira Peres, Mark William Lopes, Carlos Alberto S. Gonçalves
      Pages 751-766
  13. Back Matter
    Pages 805-820

About this book


This book illustrates remarkable roles of metal ions in the neuropathophysiology of stroke, which is a major cause of death and disability worldwide. Metal ions have unique chemical properties that allow them to play diverse roles in the brain. They regulate excitability and function as co-factors in cellular and genetic signaling pathways and therefore, have important roles ranging from essential to toxic. For the first time, the dyshomeostasis and pathophysiological actions of these metals in stroke are discussed systematically in thirty-six chapters in one volume.


Highlighted metal ions include:

Aluminum (Al)

Arsenic (As)

Cadmium (Cd)

Calcium (Ca)

Copper (Cu)

Iron (Fe)

Magnesium (Mg)

Manganese (Mn)

Mercury (Hg)

Nickel (Ni)

Potassium (K)

Selenium (Se)

Sodium (Na)

Zinc (Zn)

Editors and affiliations

  • Yang V. Li
    • 1
  • John H. Zhang
    • 2
  1. 1., Department of Biomedical SciencesOhio UniversityAthensUSA
  2. 2.Loma Linda UniversityLoma LindaUSA

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