© 2010

Invertebrate Immunity

  • Kenneth Söderhäll
  • Describes diversity between different invertebrate animal groups

  • Shows that the prophenoloxidase activating system and the induction of the Toll pathway in an insect share the same proteolytic cascade

  • Displays a growing interest in invertebrate immunity, which is the study of the link between physiology and immunity


Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 708)

Table of contents

  1. Front Matter
    Pages i-xxiv
  2. René Augustin, Thomas C. G. Bosch
    Pages 1-16
  3. Eric S. Loker
    Pages 17-43
  4. Linsheng Song, Lingling Wang, Limei Qiu, Huan Zhang
    Pages 44-65
  5. Martin Bilej, Petra Procházková, Marcela Šilerová, Radka Josková
    Pages 66-79
  6. Aurélie Tasiemski, Michel Salzet
    Pages 80-104
  7. Ilka Engelmann, Nathalie Pujol
    Pages 105-121
  8. Petr Kopáček, Ondřej Hajdušek, Veronika Burešová, Sirlei Daffre
    Pages 137-162
  9. Ji-Won Park, Chan-Hee Kim, Jiang Rui, Keun-HwaPark, Kyung-Hwa Ryu, Jun-Ho Chai et al.
    Pages 163-180
  10. Haobo Jiang, Andreas Vilcinskas, Michael R. Kanost
    Pages 181-204
  11. Julián F. Hillyer
    Pages 218-238
  12. Lage Cerenius, Pikul Jiravanichpaisal, Hai-peng Liu, Irene Soderhall
    Pages 239-259
  13. L. Courtney Smith, Julie Ghosh, Katherine M. Buckley, Lori A. Clow, Nolwenn M. Dheilly, Tor Haug et al.
    Pages 260-301
  14. Masaru Nonaka, Honoo Satake
    Pages 302-310
  15. Back Matter
    Pages 311-316

About this book


It can be seen that the insects are the still attracting most research and researchers. However, an increasing interest is emerging to study new invertebrate groups, especially those where the genome is known. Even though Drosophila has been and still is an excellent model for immune studies, it is now clear that there are great differences between immune responses in Drosophila and that of several other invertebrates, which indeed calls for more research on other invertebrates


Invertebrate Söderhäll immune response immunity immunobiology immunology infection innate immunity parasite peptides

Editors and affiliations

  • Kenneth Söderhäll
    • 1
  1. 1.Department of Comparative PhysiologyUppsala UniversityUppsalaSweden

About the editors

Keneth Söderhäll studied at Uppsala University and obtained his MSc degree in 1972 and PhD in 1978. He was promoted to associate professor (Docent) in 1980. After receiveing his PhD he worked in many different laboratories as a post‑doc or as a guest scientist at the University of Montpellier/St.Christol, the Medical Cell Biology department at Tromsö University, the Millport Marine Biological Station in Scotland, University College of Wales in Swansea, the Marine Biological Laboratory at Woods Hole and John Hopkins University. In 1986 he held a Royal Society Fellowship at Swansea. In collaboration with Valerie J. Smith, he developed a new method to isolate and separate blood cells from invertebrates,which was based on using an anticoagulant with a low pH and EDTA , a method now used to isolate most invertebrate blood cells. When he returned to Uppsala he took a position as a researcher at the Swedish Science Research Council in 1987, obtaining a chair and appointment to professor and head of department at Uppsala University in 1989. He continued with research mainly on the proPO‑system in arthropods. His group was first to clone proPO from an invertebrate and he has worked with this so‑called melanization reaction for several years. His research team has also deciphered the clotting reaction in crustaceans and shown that it consists of a clotting protein present in plasma and a clotting enzyme, a transglutaminase present in the blood cells. This clotting system is distinct from that of a horseshoe crabs’ in which a proteinase cascade demonstrates the great diversity in immune processes in invertebrates. He has published 230 original papers and 65 reviews in journals and books, and he has edited 4 books. He is presently on the editorial board on Fish and Shellfish Immunology, and is the editor of Journal of Experimental Biology. Dr. Söderhäll previously served on Journal Experimental Zoology, Animal Biology, Journal of Invertebrate Pathology and Developmental and Comparative Immunology. Since 2000 he has coedited the journal Developmental and Comparative Immunology and beginning in 2009 he is editor‑in‑chief for this journal. He was president for the International Society of Developmental and Comparative Immunology from 2006‑2009. Currently he heads the Department of Comparative Physiology at Uppsala University (

Bibliographic information

  • Book Title Invertebrate Immunity
  • Editors Kenneth Söderhäll
  • Series Title Advances in Experimental Medicine and Biology
  • DOI
  • Copyright Information Landes Bioscience and Springer Science+Business Media, LLC 2010
  • Publisher Name Springer, Boston, MA
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-1-4419-8058-8
  • eBook ISBN 978-1-4419-8059-5
  • Series ISSN 0065-2598
  • Edition Number 1
  • Number of Pages XXIV, 316
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Biomedicine, general
  • Buy this book on publisher's site
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