© 2012

Lymphoma and Leukemia of the Nervous System

  • Tracy Batchelor
  • Lisa M. DeAngelis

Table of contents

  1. Front Matter
    Pages i-xix
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Nikolai Podoltsev, Jill Lacy, Julie Vose
      Pages 3-39
    3. Mark M. Awad, Harshabad Singh, Eyal C. Attar
      Pages 41-58
  3. Central Nervous System Lymphomas

    1. Front Matter
      Pages 59-59
    2. Judith A. Ferry, Rolf Pfannl, Nancy L. Harris
      Pages 61-86
  4. Primary CNS Lymphoma

    1. Front Matter
      Pages 87-87
    2. Ingfrid Salvesen Haldorsen, Brian Patrick O’Neill
      Pages 89-97
    3. James L. Rubenstein
      Pages 99-111
    4. Tracy Batchelor, Edward Neuwelt, Daphne L. Wang, R. Gilberto Gonzalez
      Pages 113-128
    5. Tracy Batchelor, Andrew Grigg, Eckhard Thiel
      Pages 141-153
    6. Carole Soussain, Patrick Johnston, Gerald Illerhaus
      Pages 155-168
  5. Variants of CNS Lymphoma

    1. Front Matter
      Pages 169-169
    2. Silvia Montoto
      Pages 171-179
    3. Samar Issa, M. Beatriz S. Lopes, David Schiff
      Pages 181-198
    4. Andrés J.M. Ferreri, Silvia Govi, José S. Pulido
      Pages 199-218
    5. Tali Siegal, Sigal Grisariu, Batia Avni, Joachim M. Baehring
      Pages 219-229
    6. Maurilio Ponzoni, Jon Glass, Emanuele Zucca
      Pages 231-242
    7. Kristoph Jahnke, Tamara N. Shenkier, Oussama Abla
      Pages 243-263

About this book


Lymphomas and leukemias of the nervous system result in devastating neurological complications and high mortality. These malignancies may arise within the central nervous system or may disseminate to the brain or cerebrospinal fluid from a source elsewhere in the body. Early diagnosis and therapeutic intervention lead to improvement in neurological symptoms and signs and potentially improved survival. The diagnostic evaluation and treatment of lymphoma and leukemia of the nervous system differ from the standard approaches used when the disease is confined outside of the nervous system. Lymphoma and Leukemia of the Nervous System is a comprehensive review of this challenging group of diseases and should be useful for the practicing neurologist, hematologist, oncologist and for any practitioner involved in the management of these patients.


Review of the first edition


This book, the first devoted primarily to the disease (Primary CNS Lymphoma), provides a comprehensive source for the study of the clinical features, diagnostic aspects, and approaches of lymphoma treatment. Although the main focus of the book is primary central nervous system lymphoma, several contributing authors also provide high-quality chapters on the neurologic manifestations of non-Hodgkin's lymphoma, Hodgkin's disease, and plasma-cell disorders and the neurologic complications of lymphoma therapy.

This book — up-to-date, concise, and clearly written — provides a review of the disease that is more in-depth than that found even in subspecialty textbooks.


Joachim Yahalom, M.D., Department of Radiation Oncology

Memorial Sloan-Kettering Cancer Center

New England Journal of Medicine


Cancer Cancer Research Leukemia Lymphoma Nervous System

Editors and affiliations

  • Tracy Batchelor
    • 1
  • Lisa M. DeAngelis
    • 2
  1. 1., Stephen E. and Catherine Pappas Center fMassachusetts General HospitalBostonUSA
  2. 2.Dept. NeurologyMemorial Sloan-Kettering Cancer CenterNew YorkUSA

Bibliographic information

Industry Sectors
Health & Hospitals
Oncology & Hematology
Consumer Packaged Goods


From the reviews:

“Book describes fundamental principles of the management of patients with primary central nervous system (CNS) lymphoma as well as secondary involvement of CNS by systemic lymphoid neoplasia. … The wealth of scientific work conducted by hematologists, oncologists, pathologists, and other experts in the field has been resynthesized into a state-of-the-art book, which is impressively comprehensive and therefore should find place on the shelf of all medical professionals involved in the care of patients with lymphoproliferative disorders.” (A. Vranovsky, Neoplasma, Issue 1, 2013)

“This concise but comprehensive book details the diagnosis and management of lymphomas and leukemias affecting the nervous system. … this book extracts the important management issues from each specialty and presents them in this single resource. … This book has a broad clinical audience that includes neurologists, hematologists, medical oncologists, radiation oncologists, neurosurgeons, neuropathologists, hematopathologists, and neuroradiologists.” (Amaal Jilani Starling, Doody’s Book Reviews, June, 2012)