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  • Book
  • © 2011

Genes and Cardiovascular Function

  • Bridges the gap between clinical cardiology and genomic study

  • Explores the role of genes in cardiac development

  • Provides a genomic approach to the treatment of the wide spectrum of cardiovascular diseases

  • Written by established investigators, representing the world’s leading experts in the field

  • Includes supplementary material: sn.pub/extras

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Table of contents (24 chapters)

  1. Hypertension and Arrhythmias

    1. Front Matter

      Pages 159-159
    2. Genetic Basis of Salt-Sensitive Hypertension in Humans

      • Frans H. H. Leenen, Shahrier Amin, Alexandre F. R. Stewart, Frederique Tesson
      Pages 161-175
    3. Gene–Environment Interactions: Their Role in Hypertension Development

      • Jaroslav Kunes, Michaela Kadlecova, Josef Zicha
      Pages 177-184
  2. Hypertrophy and Failure

    1. Front Matter

      Pages 197-197
    2. CLP-1-Mediated Transcriptional Control of Hypertrophic Gene Programs Underlying Cardiac Hypertrophy

      • M. A. Q. Siddiqui, Michael Wagner, Jorge Espinoza-Derout, Facan Huang, Daniel Beckles, Eduardo Mascareno
      Pages 199-211
    3. Molecular Mechanisms of Subcellular Remodeling in Congestive Heart Failure

      • Andrea P. Babick, Alison L. MĂĽller, Naranjan S. Dhalla
      Pages 213-223
    4. Left Ventricular Assist Device: Morphological, Molecular, and Genetic Changes After Mechanical Support

      • Hideo A. Baba, Atsushi Takeda, Nobuakira Takeda, Jeremias Wohlschlaeger
      Pages 235-240
    5. Multi-scale, Multi-physics Heart Simulator as a Tool to Link Bench and Bedside

      • S. Sugiura, T. Washio, J. Okada, H. Watanabe, T. Hisada
      Pages 253-260
  3. Back Matter

    Pages 261-263

About this book

Rapid advances in molecular medicine have led to pronounced new developments in experimental and clinical cardiology.  In the embrace of modern molecular biology and bridging the gap between the clinical and the genomic, cardiovascular medicine has seen major strides in the understanding of the molecular mechanisms that drive disease progression.  The ability to rapidly identify candidate human genes for cardiovascular diseases lends itself to the development of diverse strategies for disease treatment and management.  The wide variety of gene expressions proffers excellent targets for novel therapeutics.  Gene therapy is steadily increasing in viability and represents a fascinating arena of research and clinical focus.

 

This book is based on two international Mendel symposia on “Genes and the Heart,” joint meetings of the Japanese and European sections of the International Academy of Cardiovascular Sciences.  Highlighting selected symposia contributions, this book explores the role of molecular biology and genetics in the basic knowledge, genesis, and clinical interventions of cardiovascular diseases.

Editors and Affiliations

  • Czech Republic, Institute of Physiology, Academy of Sciences of the, Prague, Czech Republic

    Bohuslav Ostadal

  • Jikei University School of Medicine, Tokyo, Japan

    Makoto Nagano

  • St. Boniface General Hospital, Research Centre, Institute of Cardiovascular Sciences, Winnipeg, Canada

    Naranjan S. Dhalla

Bibliographic Information

  • Book Title: Genes and Cardiovascular Function

  • Editors: Bohuslav Ostadal, Makoto Nagano, Naranjan S. Dhalla

  • DOI: https://doi.org/10.1007/978-1-4419-7207-1

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-4419-7206-4Published: 09 August 2011

  • Softcover ISBN: 978-1-4899-7804-2Published: 23 August 2016

  • eBook ISBN: 978-1-4419-7207-1Published: 09 August 2011

  • Edition Number: 1

  • Number of Pages: XVI, 264

  • Topics: Cardiology, Medical Biochemistry

  • Industry Sectors: Biotechnology, Engineering, Finance, Business & Banking, Health & Hospitals, Pharma

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access