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  • © 2011

Folding for the Synapse

  • Introduces important concepts of folding machineries.

  • Gives examples of the biological relevance of further chaperone functions.

  • Addresses the current view on how protein folding and misfolding contribute to synapse function and dysfunction.

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Table of contents (15 chapters)

  1. Chronic neurodegeneration associated with protein misfolding and synaptic dysfunction

    1. Prion Protein Misfolding at the Synapse

      • Zuzana Å iÅ¡ková, V. Hugh Perry, Ayodeji A. Asuni
      Pages 289-312
  2. Back Matter

    Pages 313-318

About this book

Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex. This book will introduce both important concepts of folding machineries and give examples of the biological relevance of further chaperone functions.

Editors and Affiliations

  • School of Biological Sciences, University of Southampton, Southampton, United Kingdom

    Andreas Wyttenbach, Vincent O'Connor

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 229.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access