BCL-2 Protein Family

Essential Regulators of Cell Death

  • Claudio Hetz

Part of the Advances in Experimental Medicine and Biology book series (volume 687)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Nika N. Danial, Alfredo Gimenez-Cassina, Daniel Tondera
    Pages 1-32
  3. Diego Rojas-Rivera, Benjamin Caballero, Sebastian Zamorano, Fernanda Lisbona, Claudio Hetz
    Pages 33-47
  4. Thanh-Trang Vo, Anthony Letai
    Pages 49-63
  5. Ross T. Weston, Hamsa Puthalakath
    Pages 65-77
  6. Luca Paoluzzi, Owen A. O’Connor
    Pages 79-96
  7. Heather M. Lamb, J. Marie Hardwick
    Pages 115-129
  8. Back Matter
    Pages 143-145

About this book


In this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL‑2 family of proteins in apoptosis, physiology and disease. An important focus of this volume is considering the potential TH ERA PEUT IC benefits of targeting apoptosis pathways in the context of human disease. Readers interested in understanding how a cell handles stress and the consequences of dysregulation of this process for human disease will find this book very valuable. It attempts to describe a fascinating area of research where physiology and biomedicine converge at different levels, revealing a trip from the molecular regulation of apoptosis to the impact of this process to the physiology of a whole organism.


Apoptosis Biomedicine Cell Hetz Protein Regulator cells dynamics physiology protein family regulation

Editors and affiliations

  • Claudio Hetz
    • 1
    • 2
  1. 1.Institute of Biomedical Sciences, FONDAP Center for Molecular Studies of the Cell (CEMC) Millennium Nucleus for Neural Morphogenesis (NEMO)University of ChileSantiagoChile
  2. 2.Department of Immunology and Infectious DiseasesHarvard School of Public HealthBostonUSA

Bibliographic information

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