© 2012

Cochlear Mechanics

Introduction to a Time Domain Analysis of the Nonlinear Cochlea


  • Addresses and explains basic differences between linear and nonlinear cochleae

  • Provides a well-justified mathematical approach, with lucid examples

  • Useful to both researchers in auditory neuroscience and students of biophysics and biomedical engineering


Table of contents

  1. Front Matter
    Pages i-xiv
  2. Anatomy and Function of the Linear Cochlea

    1. Front Matter
      Pages 1-1
    2. Hendrikus Duifhuis
      Pages 3-19
    3. Hendrikus Duifhuis
      Pages 21-31
    4. Hendrikus Duifhuis
      Pages 33-63
  3. Anatomy and Function of the Nonlinear Cochlea

    1. Front Matter
      Pages 65-65
    2. Hendrikus Duifhuis
      Pages 95-146
  4. Results and Open Issues

    1. Front Matter
      Pages 147-147
    2. Hendrikus Duifhuis
      Pages 149-174
    3. Hendrikus Duifhuis
      Pages 175-193
  5. Basic Linear and Nonlinear Tools and a PTPV Response Collection

    1. Front Matter
      Pages 195-195
    2. Hendrikus Duifhuis
      Pages 197-220
    3. Hendrikus Duifhuis
      Pages 221-235
    4. Hendrikus Duifhuis
      Pages 237-258
  6. Back Matter
    Pages 259-261

About this book


The field of cochlear mechanics has received increasing interest over the last few decades. In the majority of these studies, researchers use linear systems analysis or linear approximations of the nonlinear (NL) systems. Even though it has been clear that the intact cochlea operates nonlinearly, lack of tools for proper nonlinear analysis, and widely available tools for linear analysis still lead to inefficient and possibly incorrect interpretation of the biophysics of the cochlea. An example is the presumption that a change in cochlear stiffness at hair cell level must account for the observed change in tuning (or frequency mapping) due to prestin application. Hypotheses like this need to be addressed in a tutorial that is lucid enough to analyze and explain basic differences.

Cochlear Mechanics presents a useful and mathematically justified/justifiable approach in the main part of the text, an approach that will be elucidated with clear examples. The book will be useful to scientists in auditory neuroscience, as well as graduate students in biophysics/biomedical engineering.

Authors and affiliations

  1. 1.Faculty of MathematicsRijksuniversiteit GroningenGroningenNetherlands

Bibliographic information

Industry Sectors
Health & Hospitals


From the book reviews:

“This is an excellent book concerning nonlinear dynamics in cochlear neurophysiology. … The discussion starts to make sense from 1950-1980. The text will help audiologists, neurophysiologists, students, fellows, and professors teaching auditory sciences.” (Joseph J. Grenier,, March, 2015)