Therapeutic Applications of Cell Microencapsulation

  • José Luis Pedraz
  • Gorka Orive

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 670)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Gorka Orive, José Luis Pedraz
    Pages 1-4
  3. Edorta Santos, Jon Zarate, Gorka Orive, Rosa Ma Hernández, José Luis Pedraz
    Pages 5-21
  4. Paul de Vos, Milica Spasojevic, Marijke M. Faas
    Pages 38-53
  5. Ainhoa Murua, Gorka Orive, Rosa M Hernández, José Luis Pedraz
    Pages 54-67
  6. Christopher G. Thanos, Briannan Bintz, Dwaine F. Emerich
    Pages 80-91
  7. Brian Salmons, Walter H. Gunzburg
    Pages 92-103
  8. Grace J. Lim, Shirin Zare, Mark Van Dyke, Anthony Atala
    Pages 126-136
  9. Back Matter
    Pages 145-147

About this book


The advancement of science is ever more contingent upon the interaction of experts vast amount of scientific information being gathered every day that exceeds the ability of any one scientist to acquire. As an illustration of the frantic pace of scientific disc- more acute in the case of scientific fields at the interface of different and seemingly distant areas of study. Amidst these, the field of cell encapsulation brings together an array of diverse disciplines such as molecular biology and biopolymers, gene therapy and inorganic membranes, stem cell biology and physicochemistry, immunology and nanotechnology. Clearly, such range of topics is too broad for any individual scientist the state-of-the-art in the field of cell encapsulation. At the core of this technology, there is an interaction of physicochemical and biological elements forming three distinct layers of complexity. First, the chemistry of the biopolymer dictates the degree of protein adsorption, vascularization, tox- ity and biocompatibility of the microcapsules. Advances in biopolymer science are providing solutions to overcome existing challenges and to improve microcapsules as delivery vehicles. Second, the choice of cells, and more precisely the plethora of in determining the immune response elicited by the host to implanted microcapsules.


biomaterials cancer cell stem cells tissue

Editors and affiliations

  • José Luis Pedraz
    • 1
  • Gorka Orive
    • 1
  1. 1.Laboratory of Pharmacy and Pharmaceutical TechnologyUniversity of the Basque CountryVitoria-GasteizSpain

Bibliographic information

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