© 2010

Inflammation and Retinal Disease: Complement Biology and Pathology

  • John D. Lambris
  • Anthony P. Adamis


  • Comprehensive look at the pathology and biology of retinal inflammation

  • Written by current, respected opthamologists and eye researchers

  • Reports on age-related degeneration, gene-associations, and other physiological pathways to retinal inflammation

Conference proceedings

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 703)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Natalia Karagianni, Anthony P. Adamis
    Pages 1-7
  3. Peter F. Zipfel, Nadine Lauer, Christine Skerka
    Pages 9-24
  4. Stephen J. Perkins, Ruodan Nan, Azubuike I. Okemefuna, Keying Li, Sanaullah Khan, Ami Miller
    Pages 25-47
  5. Lizhen Ren, John Danias
    Pages 95-104
  6. Yaroslav Tsybovsky, Robert S. Molday, Krzysztof Palczewski
    Pages 105-125
  7. Bärbel Rohrer, Qin Long, Beth Coughlin, Brandon Renner, Yuxiang Huang, Kannan Kunchithapautham et al.
    Pages 137-149
  8. David C. Fritzinger, Robin Dean, Carol Meschter, Katina Wong, Roman Halter, Jürgen Borlak et al.
    Pages 151-162
  9. Back Matter
    Pages 163-167

About these proceedings


Numerous studies have pointed to the key role of complement in the pathogenesis of retinal disease, particularly age-related macular degeneration (AMD). Reports about new gene associations and links to other physiological pathways are emerging almost on a weekly base. Several promising clinical candidates covering a wide area of potential treatment applications are in the pipelines of both industrial and academic groups. This indicates an increasing interest in complement as a therapeutic target. In view of these exciting discoveries, scientists from around the world convened at the 1st Aegean Conferences Conference on Inflammation and Retinal Disease: Complement Biology and Pathology (June 10-17, 2007) in Crete, Greece, to discuss recent advances in this rapidly-evolving field. This volume represents a collection of topics on the functions of complement in eye diseases, pathophysiology, protein structures, and complement therapeutics discussed during the conference.


eye macular degeneration pathogenesis pathology retina

Editors and affiliations

  • John D. Lambris
    • 1
  • Anthony P. Adamis
    • 2
  1. 1.Department Of Pathology Laboratory Of, MedicineUniversity Of PennsylvaniaPhiladelphiaUSA
  2. 2., Department of Ophthalmology and Visual SUniversity of Illinois at ChicagoChicagoUSA

Bibliographic information

  • Book Title Inflammation and Retinal Disease: Complement Biology and Pathology
  • Editors John D. Lambris
    Anthony P. Adamis
  • Series Title Advances in Experimental Medicine and Biology
  • Series Abbreviated Title Advs Exp.Medicine,Biology
  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2010
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-1-4419-5634-7
  • Softcover ISBN 978-1-4614-2648-6
  • eBook ISBN 978-1-4419-5635-4
  • Series ISSN 0065-2598
  • Edition Number 1
  • Number of Pages XIV, 170
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Ophthalmology
  • Buy this book on publisher's site
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