© 2010

Forkhead Transcription Factors

Vital Elements in Biology and Medicine

  • Kenneth Maiese

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 665)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Insights into Immunity, Infection and Cancer

    1. Front Matter
      Pages 1-1
    2. Florent Carrette, Stéphanie Fabre, Georges Bismuth
      Pages 3-16
    3. Chang H. Kim
      Pages 17-29
    4. Alicia N. McMurchy, Sara Di Nunzio, Maria Grazia Roncarolo, Rosa Bacchetta, Megan K. Levings
      Pages 30-45
  3. Elucidating the Components Responsible for Vascular Development and Disease in the Cardiovascular System

    1. Front Matter
      Pages 61-61
    2. Albert Wong, Elizabeth A. Woodcock
      Pages 78-89
    3. Xiao-Feng Yang, Pu Fang, Shu Meng, Michael Jan, Xinyu Xiong, Ying Yin et al.
      Pages 90-105
    4. Michal Entin-Meer, Arnon Afek, Jacob George
      Pages 106-114
  4. Dissecting the Pathways of Neuronal Integration and Plasticity in the Nervous System

    1. Front Matter
      Pages 115-115
    2. Hiroshi Takahashi, Kaoru Takahashi, Fu-Chin Liu
      Pages 117-129
  5. Translating Vital Cellular Mechanisms into Successful Clinical Care

About this book


Forkhead Transcription Factors: Vital Elements in Biology and Medicine provides a unique platform for the presentation of novel work and new insights into the vital role that forkhead transcription factors play in multiple systems throughout the body. Leading international authorities provide their knowledge and insights to offer a novel perspective for translational medicine that highlights the role of forkhead genes and proteins that may have the greatest impact for the development of new strategies for a broad array of disorders. Equally important, Forkhead Transcription Factors: Vital Elements in Biology and Medicine clearly sets a precedent for the necessity to understand the diverse and complex nature of forkhead proteins since this family of transcription factors can limit as well as foster disease progression depending upon the cellular environment. The presentation and discussion of innovative studies and especially those that examine previously unexplored pathways that may influence clinical survival and longevity offer an exciting approach to address the potential of forkhead transcription factors for new therapeutic avenues in multiple disciplines.


Termination autoimmune disease biology development genes immune response immune system immunity immunology infection protein proteins reproduction transcription translation

Editors and affiliations

  • Kenneth Maiese
    • 1
    • 2
    • 3
    • 4
    • 5
    • 6
  1. 1.Division of Cellular and Molecular Cerebral IschemiaWayne State University School of MedicineDetroitUSA
  2. 2.Department of NeurologyWayne State University School of MedicineDetroitUSA
  3. 3.Department of Anatomy and Cell BiologyWayne State University School of MedicineDetroitUSA
  4. 4.Barbara Ann Karmanos Cancer InstituteWayne State University School of MedicineDetroitUSA
  5. 5.Center for Molecular Medicine and GeneticsWayne State University School of MedicineDetroitUSA
  6. 6.Institute of Environmental Health SciencesWayne State University School of MedicineDetroitUSA

About the editors

KENNETH MAIESE is a physicianscientist whose interests focus on the basic and clinical mechanisms that control neuronal and vascular longevity and immune system function. He presently is the Chief of the Division of Cellular and Molecular Cerebral Ischemia and is a Professor in the Departments of Neurology and Anatomy and Cell Biology, the Center for Molecular Medicine and Genetics, the Barbara Ann Karmanos Cancer Institute, and the National Institute of Environmental Health Sciences at Wayne State University School of Medicine.

Dr. Maiese graduated from the University of Pennsylvania Suma cum Laude with Distinction and received his medical degree as a Teagle and Grupe Foundation Scholar from Weill Medical College of Cornell University. He obtained his internship and residency at The New York Hospital-Cornell Medical Center and subsequently completed his clinical and basic science postdoctoral training at Cornell and the National Institute of Aging.

Dr. Maiese has been fortunate to receive recognition with outstanding teaching awards and election to America’s Top Physicians and The Best of U.S. Physicians. His investigations are designed to translate basic science into successful therapeutic treatments for conditions such as cancer, metabolic disorders, cardiovascular disease, diabetes, stroke, and Alzheimer’s disease. His work has received the distinction of “High Impact Research and Potential Public Health Benefit” by the National Institutes of Health with continuous funding from sources that include the American Diabetes Association, the American Heart Association, the Bugher Foundation, a Johnson and Johnson Focused Giving Award, and the National Institutes of Health. He chairs national grant committees and is a chartered panel member or consultant for several national and international foundations as well as multiple study sections and special emphasis panels for the National Institutes of Health.

Dr. Maiese serves as the Editor-in-Chief for two international journals as well an Associate Editor or a member of the editorial board for several journals, executive committees, technology transfer panels, and scientific advisory councils. Given the broad applications of his work, Dr. Maiese is frequently honored as the chairperson and/or the plenary speaker for a number of international symposiums in a range of disciplines that include cell biology, neuroscience, vascular biology, cardiac disease, molecular oncology, and renal physiology.

Bibliographic information

  • Book Title Forkhead Transcription Factors
  • Book Subtitle Vital Elements in Biology and Medicine
  • Editors Kenneth Maiese
  • Series Title Advances in Experimental Medicine and Biology
  • DOI
  • Copyright Information Springer-Verlag New York 2010
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-1-4419-1598-6
  • Softcover ISBN 978-1-4614-2489-5
  • eBook ISBN 978-1-4419-1599-3
  • Series ISSN 0065-2598
  • Edition Number 1
  • Number of Pages , 292
  • Number of Illustrations 44 b/w illustrations, 3 illustrations in colour
  • Topics Biomedicine, general
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Consumer Packaged Goods