© 2010

Computational Cardiovascular Mechanics

Modeling and Applications in Heart Failure

  • Julius M. Guccione
  • Ghassan S. Kassab
  • Mark B. Ratcliffe


  • Edited and authored by experts in the field, with both an engineering and clinical background

  • Identifies key links between engineering tools and clinical applications

  • First book to address this topic from a computational cardiac mechanics perspective


Table of contents

  1. Front Matter
    Pages i-xxvii
  2. Computational Modeling of Cardiovascular Mechanics

    1. Front Matter
      Pages 1-1
    2. Jonathan F. Wenk, Choon-Sik Jhun, Zhihong Zhang, Kay Sun, Mike Burger, Dan Einstein et al.
      Pages 3-21
    3. Edward W. Hsu, Lindsey J. Healy, Daniel R. Einstein, Andrew P. Kuprat
      Pages 23-39
    4. Choon-Sik Jhun, Jonathan F. Wenk, Kay Sun, Julius M. Guccione
      Pages 41-54
    5. Jonathan F. Wenk, Choon-Sik Jhun, Kay Sun, Nielen Stander, Julius M. Guccione
      Pages 55-72
    6. Mark Svendsen, William Combs, Edward J. Berbari, Ghassan Kassab
      Pages 73-88
    7. Ghassan S. Kassab
      Pages 89-102
    8. Thomas Wischgoll, Daniel R. Einstein, Andrew P. Kuprat, Xiangmin Jiao, Ghassan S. Kassab
      Pages 103-119
    9. Yunlong Huo, Ghassan S. Kassab
      Pages 121-139
    10. Henry Y. Chen, Luoding Zhu, Yunlong Huo, Yi Liu, Ghassan S. Kassab
      Pages 141-157
  3. Applications in Heart Failure

    1. Front Matter
      Pages 177-177
    2. Liang Zhong, Ru San Tan, Yi Su, Si Yong Yeo, Terrace Chua, Tian Hai Koh et al.
      Pages 179-196
    3. Jonathan F. Wenk, Choon-Sik Jhun, Kay Sun, Mark B. Ratcliffe, Julius M. Guccione
      Pages 197-210
    4. Choon-Sik Jhun, Namrata Gundiah, Kay Sun, Hani N. Sabbah, E. Elaine Tseng, Mark B. Ratcliffe et al.
      Pages 211-226
    5. Samuel T. Wall, Jonathan F. Wenk, Choon-Sik Jhun, Julius M. Guccione
      Pages 227-238
    6. Laura R. Croft, Mohammad R. Kaazempur Mofrad
      Pages 255-275
    7. Meena Sankaranarayanan, Dhanjoo N. Ghista, Leok Poh Chua, Tan Yong Seng, Kannan Sundaravadivelu, Ghassan S. Kassab
      Pages 277-295

About this book


Computational Cardiovascular Mechanics promotes the application of patient-specific cardiovascular mechanics models to clinical medicine, which aid medical diagnosis and enhance treatment for cardiovascular disease.

Organized in a two-part structure, this volume presents a comprehensive overview of computational modeling from both solid mechanics and fluid dynamics perspectives. Part I offers chapters devoted to various techniques involving finite element modeling of ventricular mechanics and computational fluid dynamics, with a focus in cardiovascular mechanics. Part II covers heart failure applications which utilize techniques in solid mechanics and fluid dynamics. In the former, both diagnostic (i.e., global and regional indices of myocardial contractility) as well as therapeutic approaches (surgical ventricular remodeling procedures, passive ventricular constraint devices, ventricular implantation of biomaterials and cardiac resynchronization therapy) are discussed. In the latter, the fluid mechanics of heart valves is simulated, as are surgical procedures and heart failure-related devices in the form of coronary artery bypass grafting and ventricular assist devices.

Computational Cardiovascular Mechanics is a vital resource for cardiovascular disease researchers who want to learn how to apply computational fluid and/or solid mechanics to the diagnosis and treatment of heart failure.


Bypass Implantat biomaterial cardiovascular cardiovascular system computational fluid dynamics constitutive equation dynamics finite element method fluid dynamics heart mechanical engineering mechanics solid turbulence

Editors and affiliations

  • Julius M. Guccione
    • 1
  • Ghassan S. Kassab
    • 2
  • Mark B. Ratcliffe
    • 3
  1. 1.Veterans Affairs Medical CenterUniversity of California, San FranciscoSan FranciscoU.S.A.
  2. 2.Purdue University IndianapolisIndiana UniversityIndianapolisU.S.A.
  3. 3.Veterans Affairs Medical CenterUniversity of California, San FranciscoSan FranciscoU.S.A.

Bibliographic information

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