Molecular Mechanisms of Spondyloarthropathies

  • Carlos López-Larrea
  • Roberto Díaz-Peña

Part of the Advances in Experimental Medicine and Biology book series (volume 649)

Table of contents

  1. Front Matter
    Pages i-xxv
  2. Ruth Wittoek, Herman Mielants
    Pages 1-16
  3. Walter P. Maksymowych
    Pages 17-36
  4. Jácome Brugues Armas, Ana Rita Couto, Bruno Filipe Bettencourt
    Pages 37-56
  5. Michael Benjamin, Dennis McGonagle
    Pages 57-70
  6. Bernard Vandooren, Paul P. Tak, Dominique Baeten
    Pages 71-84
  7. Chun-Hsiung Chen, David Tak Yan Yu, Chung-Tei Chou
    Pages 122-132
  8. Jürgen Braun
    Pages 133-147
  9. Matthew A. Brown
    Pages 148-158
  10. Simon J. Powis, Susana G. Santos, Antony N. Antoniou
    Pages 210-216
  11. Robert A. Colbert, Monica L. DeLay, Gerlinde Layh-Schmitt, Dawn P. Sowders
    Pages 217-234
  12. Anna S. Sahlberg, Kaisa Granfors, Markus A. Penttinen
    Pages 235-244
  13. Joel D. Taurog
    Pages 245-254
  14. J. S. Hill Gaston, Lorna B. Jarvis, Libin Zhang, Jane C. Goodall
    Pages 263-276
  15. Roberto Díaz-Peña, Miguel Ángel Blanco-Gelaz, Carlos López-Larrea
    Pages 286-299
  16. Back Matter
    Pages 311-314

About this book


It is now over ten years since we edited the first edition of HLA-B27 in the Development of Spondyloarthropathies (SpA). It is obvious that over this period an enormous amount of information concerning SpA and HLA-B27 has accumulated, and this has been reflected in the knowledge of molecular mechanism of the spondyloarthropathies. Discussion for such a book took initial form at the outstanding 4th Gent Symposium on SpA in October 2006, but was not formally commissioned by Landes Bioscience until early 2007. Molecular Mechanisms of Spondyloarthropathies aims to synthesize this growing knowledge and present all the current studies concerning the basic research of SpA.

Over the last decade, enormous progress has been made in the understanding of the molecular and cellular processes that lead to disease pathology. Recognition of the pathways involved in the pathogenic mechanisms of disease and the potential to target specific immune effector functions have opened the door to a wide range of innovative treatment opportunities for the SpA. Thus, we believe that the understanding of the specific molecular mechanisms involved would help to design highly specific drugs in the future. The contributors are among the best in their field and reflect the state of the art of research and current opinion of rheumatologists and immunologists.


Arthritis Arthropathie imaging immunity inflammation joint pathology peptides rheumatoid arthritis

Editors and affiliations

  • Carlos López-Larrea
    • 1
  • Roberto Díaz-Peña
    • 1
  1. 1.Hospital Universitario Central de AsturiasOviedoSpain

Bibliographic information

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