Pediatric and Adolescent Osteosarcoma

  • Norman Jaffe
  • Oyvind S. Bruland
  • Stefan Bielack

Part of the Cancer Treatment and Research book series (CTAR, volume 152)

Table of contents

  1. Front Matter
    Pages i-xx
  2. General Aspects of Osteosarcoma

    1. Front Matter
      Pages 1-1
    2. Giulia Ottaviani, Norman Jaffe
      Pages 3-13
    3. Giulia Ottaviani, Norman Jaffe
      Pages 15-32
    4. A. Kevin Raymond, Norman Jaffe
      Pages 85-121
  3. Treatment

    1. Front Matter
      Pages 124-124
    2. Alan W. Yasko
      Pages 125-145
    3. Rudolf Schwarz, Oyvind Bruland, Anna Cassoni, Paula Schomberg, Stefan Bielack
      Pages 147-164
  4. Review of the Past, Impact on the Future

    1. Front Matter
      Pages 218-218
    2. Norman Jaffe
      Pages 219-237
    3. Stefano Ferrari, Emanuela Palmerini, Eric L. Staals, Mario Mercuri, Bertoni Franco, Piero Picci et al.
      Pages 275-287
    4. Stefan Bielack, Herbert Jürgens, Gernot Jundt, Matthias Kevric, Thomas Kühne, Peter Reichardt et al.
      Pages 289-308
    5. Øyvind S. Bruland, Henrik Bauer, Thor Alvegaard, Sigbjørn Smeland
      Pages 309-318
    6. İnci Ayan, Rejin Kebudi, Harzem Özger
      Pages 319-338
    7. N. Marina, S. Bielack, J. Whelan, S. Smeland, M. Krailo, M. R. Sydes et al.
      Pages 339-353
    8. Robert S. Benjamin, Shreyaskumar R. Patel
      Pages 355-363
  5. Supportive Care and Quality of Life

  6. Research and Investigation: New and Innovative Strategies

  7. Back Matter
    Pages 573-591

About this book


Pediatric and Adolescent Osteosarcoma provides a review of the nature of osteosarcoma and the conflict that accompanied the introduction of adjuvant therapy for osteosarcoma culminating in accepted and prevailing methods of current therapy. It outlines concepts in epidemiology and etiology, and provides chapters on pathology and radiologic characteristics of osteosarcoma, surgical therapy tailored specifically for treatment of primary tumors in pediatric/adolescent age groups, treatment of pulmonary and extra pulmonary metastases and complications, as well as the role of radiation therapy. The volume concludes with a review of differences and similarities in the management of osteosarcoma in adults as compared to pediatrics / adolescents and new laboratory and animal investigations currently in progress to develop effective diagnostic and therapeutic approaches to improve the outcome.

In essence the scope and intensive coverage of the book provides a historical perspective of the advances made over the past 30 years and emerging concepts and prospects for new diagnostic and therapeutic approaches. This is based upon past experiences and new discoveries. It also provides a unique opportunity for pediatric and adult medical oncologists, physicians in training, orthopedic surgeons, pathologists, radiologists, radiotherapists, oncology nurses and allied professionals involved in the care of pediatric/adolescent patients with osteosarcoma to become acquainted with prevailing methods of treatment and new and evolving concepts and developments.


"Osteosarcoma is the most common primary bone malignancy.  Remarkable advances have occurred in the management of this cancer over the last two decades.  In this text experts in the field discuss the most pertinent biologic and clinical issues relevant to the disease."

Steven T. Rosen, M.D.
Series Editor


Rehabilitation Staging adjuvant therapy bone sarcomas classification osteosarcoma soft tissue sarcomas

Editors and affiliations

  • Norman Jaffe
    • 1
  • Oyvind S. Bruland
    • 2
  • Stefan Bielack
    • 3
  1. 1.MD Anderson Cancer CenterUniversity of TexasHoustonU.S.A.
  2. 2.Dept. Medical OncologyNorwegian Radium HospitalOsloNorway
  3. 3.Orthopädische KlinikOlgahospitalStuttgartGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 2010
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-1-4419-0283-2
  • Online ISBN 978-1-4419-0284-9
  • Series Print ISSN 0927-3042
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology