Bone Metastases

A translational and clinical approach

  • Dimitrios Kardamakis
  • Vassilios Vassiliou
  • Edward Chow

Part of the Cancer Metastasis – Biology and Treatment book series (CMBT, volume 12)

Table of contents

  1. Front Matter
    Pages I-XVI
  2. Fundamental Concepts of Bone Metastases

    1. Front Matter
      Pages 1-1
    2. Vassiliki Tzelepi, Athanassios C. Tsamandas, Vassiliki Zolota, Chrisoula D. Scopa
      Pages 3-30
    3. G. David. Roodman
      Pages 31-50
    4. Pelagia G. Tsoutsou, Michael I. Koukourakis
      Pages 51-76
    5. Vassilios Vassiliou, Edward Chow, Dimitrios Kardamakis
      Pages 77-92
    6. Janet E. Brown, Edward Chow
      Pages 93-116
  3. Imaging Modalities

    1. Front Matter
      Pages 117-117
    2. Christina Kalogeropoulou, Anna Karachaliou, Peter Zampakis
      Pages 119-136
    3. Andor Glaudemans, Marnix Lam, Niels Veltman, Rudi Dierckx, Alberto Signore
      Pages 137-162
    4. Ekaterini Solomou, Alexandra Kazantzi, Odysseas Romanos, Dimitrios Kardamakis
      Pages 163-181
  4. Therapeutic Strategies

    1. Front Matter
      Pages 183-183
    2. Jan W.H. Leer, Yvette van der Linden
      Pages 185-193
    3. Fred Saad, Arif Hussain
      Pages 195-231
    4. Vassilios Vassiliou, Dimitrios Kardamakis
      Pages 233-250
    5. Markku Nousiainen, Cari Whyne, Albert Yee, Joel Finkelstein, Michael Ford
      Pages 263-286
    6. Thomas Makatsoris, Haralabos P. Kalofonos
      Pages 287-298
    7. Konstantinos Kamposioras, Evangelos Briasoulis
      Pages 299-320
    8. Giovanni Storto
      Pages 321-341
  5. Assessment of Therapeutic Response

    1. Front Matter
      Pages 343-343
    2. Orit Freedman, Mark Clemons, Vassilios Vassiliou, Dimitrios Kardamakis, Christine Simmons, Mateya Trinkaus et al.
      Pages 345-370
    3. Amanda Hird, Edward Chow
      Pages 371-394
  6. Back Matter
    Pages 395-400

About this book


"Bone Metastases: A Translational and Clinical Approach" serves as both an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume:

  • describes the molecular and cellular mechanisms involved in the formation of bone metastases,
  • comments on the role of angiogenesis,
  • presents the newer advances made in the understanding of the clinical picture and symptoms of patients,
  • analyses the role of bone markers in research and clinical practice
  • deals with all aspects of imaging modalities applied for the detection and evaluation of bone metastases.

This volume also covers the use of radiotherapy, surgery and systemic treatments for the management of metastatic bone disease and new therapeutic approaches. Moreover it may also serve as a guide for the clinical and therapeutic management of patients with metastatic bone disease.

Overall this volume presents a thorough overview of all aspects of metastatic bone disease and provides a comprehensive and concise information resource for medical researchers, oncologists, orthopaedic surgeons and clinicians.


angiogenesis bisphosphonates chemotherapy clinical trial computed tomography (CT) hormones imaging magnetic resonance imaging (MRI) metastasis necrosis pathophysiology physiology prevention radiotherapy surgery

Editors and affiliations

  • Dimitrios Kardamakis
    • 1
  • Vassilios Vassiliou
    • 1
  • Edward Chow
    • 2
  1. 1.Dept. of Radiation OncologyUniversity of Patras Medical SchoolPatrasGreece
  2. 2.Dept. of Radiation OncologyUniversity of Toronto Sunnybrook Health Sciences CentreTorontoCanada

Bibliographic information

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