General Principles of Tumor Immunotherapy

Basic and Clinical Applications of Tumor Immunology

  • Howard L. Kaufman
  • Jedd D. Wolchok

Table of contents

  1. Front Matter
    Pages I-XII
  2. General Principles of Tumor Immunology

    1. Front Matter
      Pages 1-1
    2. Michael A. Morse, Timothy M. Clay, H Kim Lyerly
      Pages 17-31
    3. Leisha A. Emens
      Pages 33-53
    4. Yvonne M. Saenger, Robert R. Jenq, Miguel-Angel Perales
      Pages 67-121
    5. Barbara Seliger, Soldano Ferrone
      Pages 123-144
    6. Theresa L. Whiteside
      Pages 145-167
  3. Tumor Vaccines

    1. Front Matter
      Pages 169-169
    2. Raymond M. Wong, Jeffrey S. Weber
      Pages 171-192
    3. Adam D. Cohen, Jedd D. Wolchok
      Pages 193-215
    4. Douglas W. Grosenbach, Jarett Feldman, Jeffrey Schlom, Scott I. Abrams
      Pages 217-250
    5. Sylvia Adams, Nina Bhardwaj, David W. O’Neill
      Pages 251-274
    6. Mark B. Faries, Donald L. Morton
      Pages 275-295
    7. Philip O. Livingston, Govind Ragupathi
      Pages 297-317
  4. Passive Immunotherapy Approaches

    1. Front Matter
      Pages 319-319
    2. Joseph G. Jurcic, Deborah A. Mulford, David A. Scheinberg
      Pages 321-342
    3. Karl S. Peggs, Sergio A. Quezada, James P. Allison
      Pages 363-390
  5. Clinical Tumor Immunotherapy

    1. Front Matter
      Pages 391-391
    2. Mary L. Disis, Keith L. Knutson
      Pages 393-404
    3. Stergios J. Moschos, John M. Kirkwood
      Pages 405-430
    4. Christian A. Petrulio, Gail DeRaffele, Howard L. Kaufman
      Pages 431-452
    5. Christoph Rader, Michael R. Bishop
      Pages 453-484
    6. Irma Larma, Robbert G. van der Most, Richard A. Lake
      Pages 485-498
  6. Back Matter
    Pages 499-503

About this book


"General Principles of Tumor Immunotherapy: Basic and Clinical Applications of Tumor Immunology" brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. This information will be invaluable to both students of immunology and cancer research and practicing physicians who have patients with cancer. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens.


Antigen DNA bacteria cancer cell clinical trial immune response immunity immunology immunotherapy interferon peptides research tumor vaccine

Editors and affiliations

  • Howard L. Kaufman
    • 1
  • Jedd D. Wolchok
    • 2
  1. 1.The Tumor Immunology LaboratoryDivision of Surgical Oncology, Columbia UniversityNew York
  2. 2.Department of Medicine, Memorial Sloan-Kettering Cancer CenterWeill Medical College of Cornell UniversityNew York

Bibliographic information

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