Table of contents

  1. Front Matter
    Pages i-xii
  2. Jack S. Cohen
    Pages 1-6
  3. Paul S. Miller
    Pages 79-95
  4. C. A. Stein, Jack S. Cohen
    Pages 97-117
  5. B. Rayner, C. Malvy, J. Paoletti, B. Lebleu, C. Paoletti, J.-L. Imbach
    Pages 119-136
  6. D. G. Knorre, V. V. Vlassov, V. F. Zarytova
    Pages 173-196
  7. Gerald Zon
    Pages 233-247
  8. Back Matter
    Pages 249-255

About this book


This first-ever book on oligodeoxynucleotides describes in detail the new antisense approach to chemotherapy. It is written by world experts, covers all areas of current knowledge and includes new results. The principle of the antisense approach is that an antisense mRNA base sequence will bind to its target mRNA base sequence and thus bring about the selective inhibition of gene expression. The antisense approach is important in general in understanding gene function, and more specifically as a potential basis for new drugs, notably against cancer and viral genes.


cancer cell DNA gene gene expression genes nucleic acid nucleotide

Editors and affiliations

  • Jack S. Cohen
    • 1
  1. 1.National Cancer InstituteNational Institutes of HealthBethesdaUSA

Bibliographic information

  • Book Title Oligodeoxynucleotides
  • Book Subtitle Antisense Inhibitors of Gene Expression
  • Editors Jack S Cohen
  • Series Title Topics in Molecular and Structural Biology
  • DOI
  • Copyright Information Macmillan Publishers Limited 1989
  • Publisher Name Palgrave, London
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-0-333-49211-6
  • Softcover ISBN 978-1-349-10871-8
  • eBook ISBN 978-1-349-10869-5
  • Edition Number 1
  • Number of Pages XII, 255
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Additional Information Previously published under the imprint Palgrave
  • Topics Molecular Medicine
    Cell Biology
    Gene Expression
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals