About this book
This book serves as a guide for identifying and applying commonly used cell-based translational assays as well as for assessing the therapeutic potential of new immuno-oncology therapeutics and advancing their mechanism of action. The detailed chapters within will provide readers with a baseline understanding of the pros and cons as well as key considerations for applying assays that are more reflective of the human immune-tumor microenvironment in order to increase their translatability into the clinic. Written for the Methods in Pharmacology and Toxicology series, the contents of this volume include the kind of specifics and real-world implementation advice to ensure success in the lab.
Authoritative and practical, Immuno-Oncology: Cellular and Translational Approaches aims to aid researchers working on biotechnology and pharmaceutical efforts to search for the next generation of safer and more effective cancer immunotherapeutics.
The chapter “Considerations in Developing Reporter Gene Bioassays for Biologics” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Cancer immunotherapy Drug discovery Cell-based translational assays Precision medicine Immune-tumor microenvironment Biosamples Immunotherapeutics
Editors and affiliations
- DOI https://doi.org/10.1007/978-1-0716-0171-6
- Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2020
- Publisher Name Humana, New York, NY
- eBook Packages Springer Protocols
- Print ISBN 978-1-0716-0170-9
- Online ISBN 978-1-0716-0171-6
- Series Print ISSN 1557-2153
- Series Online ISSN 1940-6053
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