© 2012

Sjögren’s Syndrome

Diagnosis and Therapeutics

  • Manuel Ramos-Casals
  • John H. Stone
  • Haralampos M. Moutsopoulos

Table of contents

  1. Front Matter
    Pages i-xx
  2. Scientific Basis

    1. Front Matter
      Pages 1-1
    2. Yannis Alamanos, Alexandros A. Drosos
      Pages 3-9
    3. Christopher J. Lessard, John A. Ice, Jacen Maier-Moore, Courtney G. Montgomery, Hal Scofield, Kathy L. Moser
      Pages 11-31
    4. Athanasios G. Tzioufas, Efstathia K. Kapsogeorgou, Menelaos N. Manoussakis, Haralampos M. Moutsopoulos
      Pages 33-53
    5. Manuel Ramos-Casals, Albert Bové, Rafael Belenguer, Xavier Forns, Salvatore de Vita
      Pages 55-66
    6. Jacques-Olivier Pers, Sophie Hillion, Gabriel Tobón, Valérie Devauchelle, Alain Saraux, Pierre Youinou
      Pages 67-82
  3. Clinical Manifestations

    1. Front Matter
      Pages 83-83
    2. Crispian Scully, Eleni A. Georgakopoulou
      Pages 85-106
    3. Stephen C. Pflugfelder, Karyn Siemasko, Michael E. Stern
      Pages 107-120
    4. Rohan R. Walvekar, Francis Marchal
      Pages 121-128
    5. Barbara M. Segal
      Pages 129-148
    6. Guillermo J. Pons-Estel, Bernardo A. Pons-Estel, Graciela S. Alarcón
      Pages 149-155
    7. Hobart W. Walling, Richard D. Sontheimer
      Pages 157-171
    8. George E. Fragoulis, Haralampos M. Moutsopoulos, John H. Stone
      Pages 173-183
    9. George E. Tzelepis, Clio P. Mavragani, Haralampos M. Moutsopoulos
      Pages 185-194
    10. Clio P. Mavragani, George E. Tzelepis, Haralampos M. Moutsopoulos
      Pages 195-208
    11. Fredrick M. Wigley
      Pages 209-225
    12. Manuel Ramos-Casals, José Rosas, Roser Solans, Margit Zeher, Peter Szodoray
      Pages 227-235
    13. George E. Fragoulis, Fotini N. Skopouli, Carlo Selmi, M. Eric Gershwin
      Pages 237-246

About this book


Sjögren’s Syndrome: Diagnosis and Therapeutics provides a thorough, multisystemic overview of the clinical manifestations of Sjögren’s Syndrome. It contains chapters pertinent across the range of medical specialties that may encounter Sjögren’s Syndrome cases. Chapters are specialty-specific, for easy reference by the relevant medical specialist.
In addition to being a diagnostic guide, Sjögren’s Syndrome: Diagnosis and Therapeutics  includes a section on prognosis and outcomes of Sjögren’s Syndrome patients and provides an exhaustive therapeutic update, focused on new agents and experimental techniques. The inclusion of diagnostic/therapeutic algorithms illustrates the text with clinical photographs of the main organs involved and helps the reader to make guided diagnostic and therapeutic decisions through decision-based algorithms.


Sjögren's syndrome

Editors and affiliations

  • Manuel Ramos-Casals
    • 1
  • John H. Stone
    • 2
  • Haralampos M. Moutsopoulos
    • 3
  1. 1.Barcelona, SurgeyHospital ClinicBarcelonaSpain
  2. 2.Massachusetts General HospitalBostonUSA
  3. 3.National University of AthensAthensGreece

About the editors

Manuel Ramos Casals, MD, PhD is a Consultant of the Department of Systemic Autoimmune Diseases, Hospital Clínic, Barcelona, Head of the "Josep Font" Laboratory of Autoimmune Diseases of the IDIBAPS, Hospital Clinic, Barcelona and Assistant Professor, Department of Medicine, University of Barcelona, Barcelona, Spain. He has published more than 100 original articles focused on Sjögren’s syndrome and related conditions, has edited 6 books on systemic autoimmune diseases and has received several national grants to investigate autoimmune diseases.

John H. Stone, MD, MPH is Clinical Director of Rheumatology, Harvard Medical School, Boston, MA, USA and the Chairman of the International Network for the Study of the Systemic Vasculitides (INSSYS). Dr Stone's research interests relate to translational investigations in systemic vasculitis. He has directed two multicenter clinical trials in Wegener's granulomatosis and antineutrophil cytoplasmic antibody-associated vasculitis, the Wegener's Granulomatosis Etanercept Trial (WGET) and the Rituximab in ANCA-associated Vasculitis (RAVE) trial. His other research efforts relate to the identification of new biomarkers through proteomic approaches, and to the development of clinical trials' outcome measures in rheumatic autoimmune diseases.

Haralampos M. Moutsopoulos, MD, FACP, FRCP is a Professor and Head of the Department of Pathophysiology, Medical School, University of Athens, Greece. He has contributed to current understanding of the clinical aspects, pathogenesis and therapy of autoimmune rheumatic disorders. He is considered a world authority on Sjögren's syndrome (autoimmune epithelitis). His scientific work is extensively cited and he has been presented with numerous national and international awards.

The Editors have extensive experience in the management of the main systemic autoimmune diseases, such as systemic lupus erythematosus, vasculitis and especially Sjögren’s syndrome. They have developed many clinical and basic research projects and, in the last 5 years, have published many reports on Sjögren’s syndrome and other autoimmune diseases in the leading journals in rheumatology and internal medicine.

Bibliographic information

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From the reviews:

“This is a detailed examination of Sjogren’s syndrome, from pathogenesis to diagnosis and treatment of the disease. One of the book’s greatest strengths is its utility as a reference. … appropriate for students, residents, and practitioners, but especially for practicing rheumatologists. … the book is quite enjoyable and easy to read cover-to-cover. The writing is clear and the subject is covered thoroughly. … This is probably the most outstanding, authoritative book on the subject that I have encountered. Any rheumatologist could benefit from reading it.” (Jonathan Miner, Doody’s Review Service, February, 2013)