• Giovanni Coticchio
  • David F. Albertini
  • Lucia De Santis

Table of contents

  1. Front Matter
    Pages i-xii
  2. Imaging

    1. Front Matter
      Pages 1-1
    2. S. Darlene Limback, David F. Albertini
      Pages 3-16
  3. Folliculogenesis and Oogenesis

    1. Front Matter
      Pages 17-17
    2. Maria Cristina Guglielmo, David F. Albertini
      Pages 63-73
    3. Martin M. Matzuk, Qinglei Li
      Pages 75-92
    4. Sergio Romero, Sandra Sanfilippo, Johan Smitz
      Pages 109-126
  4. The (Epi)Genetic Making of the Oocyte

    1. Front Matter
      Pages 127-127
    2. Swamy K. Tripurani, Stephanie A. Pangas
      Pages 129-139
    3. Maurizio Zuccotti, Valeria Merico, Carlo Alberto Redi, Silvia Garagna
      Pages 141-150
  5. Oocyte Meiosis and Cytoplasmic Dynamics

    1. Front Matter
      Pages 169-169
    2. Keith T. Jones, Simon I. R. Lane, Janet E. Holt
      Pages 183-193
    3. Marie-Hélène Verlhac, Manuel Breuer
      Pages 195-207
    4. Lucia De Santis, Tiziana A. L. Brevini
      Pages 209-217
    5. Liborio Stuppia
      Pages 219-227
  6. Oocyte Developmental Potential

    1. Front Matter
      Pages 229-229
    2. Mourad Assidi, Marc-André Sirard
      Pages 231-252
    3. Anna Ajduk, Agnieszka Jedrusik, Magdalena Zernicka-Goetz
      Pages 253-264
    4. Giovanni Coticchio, Fausta Brambillasca
      Pages 289-306
    5. Catherine M. H. Combelles, Vanesa Y. Rawe
      Pages 307-327
    6. Miguel A. Velazquez, Tom P. Fleming
      Pages 329-351
  7. Giovanni Coticchio, David F. Albertini, Lucia De Santis, Ospedale S. Raffaele
    Pages E1-E1
  8. Back Matter
    Pages 353-364

About this book


The oocyte is the largest and most mysterious cell in the body of mammalian organisms. Through its growth and maturation, it reaches extreme levels of specialization, while maintaining at the same time a condition of totipotency. Its unique ability, in co-operation with the spermatozoon, to give rise to a fully developed organism formed from hundreds of different tissues and myriads of individual cells has inspired intellectuals of all ages.

Oogenesis finds impetus and purpose in casting scientific perspective towards this unique cell for the benefit of scientists and assisted reproductive technology (ART) specialists. The authors of the chapters are distinguished authorities in their respective areas of competence.

From the opening of the book the reader is lead on a fantastic voyage from the formation of the primordial oocyte to the development of the early embryo, passing through crucial processes of oogenesis, such as co-ordination of oocyte and follicle growth, gene expression and organelle reorganization during growth and maturation, epigenetic mechanisms, regulation of meiosis, totipotency, cell polarity, oogenesis in vitro and maternal regulation of early development.


Embryo Follicle Mammalian Oogenesis Oocyte Oogenesis Primordial Oocyte

Editors and affiliations

  • Giovanni Coticchio
    • 1
  • David F. Albertini
    • 2
  • Lucia De Santis
    • 3
  1. 1.BIOGENESI, Instituti Clinici ZucchiMonzaItaly
  2. 2.University of Kansas Medical CenterKansas CityUSA
  3. 3.Ospedale S. Raffaele, Department of Ob/GynUniversity Vita-SaluteMilanItaly

Bibliographic information

Industry Sectors
Health & Hospitals