© 2010

Ovarian Cancer

Second Edition

  • M. Sharon Stack
  • David A. Fishman


  • New advances in ovarian cancer detection and treatment

  • Provides an analysis of current research into aspects of malignant transformation, growth control and metastasis


Part of the Cancer Treatment and Research book series (CTAR, volume 149)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Chemoprevention, Staging, and Novel Therapeutic Targets

    1. Front Matter
      Pages 1-1
    2. Anna Hoekstra, Gustavo C. Rodriguez
      Pages 3-34
    3. Mario M. Leitao Jr, Richard R. Barakat
      Pages 35-61
    4. John Farley, Michael J. Birrer
      Pages 63-84
    5. Mary Clouser, Lisa M. Hess, Setsuko K. Chambers
      Pages 85-105
  3. Tumorigenesis and Biomarkers

    1. Front Matter
      Pages 107-107
    2. Zhen Lu, Robert C. Bast Jr
      Pages 109-129
    3. Kenneth P. Nephew, Curt Balch, Shu Zhang, Tim H-M. Huang
      Pages 131-146
    4. Elizabeth R. Smith, Kathy Qi Cai, Callinice D. Capo-chichi, Xiang- Xi Xu
      Pages 147-163
    5. George M. Yousef, Eleftherios P. Diamandis
      Pages 165-187
    6. Andre T. Baron, Jacqueline M. Lafky, Cecelia H. Boardman, Elsa M. Cora, Marites C. Buenafe, Dachao Liu et al.
      Pages 189-202
    7. Laurie G. Hudson, Reema Zeineldin, Melina Silberberg, M. Sharon Stack
      Pages 203-226
  4. Tumor Progression, Metastasis, Research Models

    1. Front Matter
      Pages 227-227
    2. Kwai Wa Cheng, Roshan Agarwal, Gordon B. Mills
      Pages 229-240
    3. Yan Xu, Dongmei Wang, Zeneng Wang
      Pages 241-267
    4. Fengqiang Wang, David A. Fishman
      Pages 269-296
    5. Wafic M. ElMasri, Giovanna Casagrande, Ebony Hoskins, Daniel Kimm, Elise C. Kohn
      Pages 297-318
    6. Maria V. Barbolina, Natalie M. Moss, Suzanne D. Westfall, Yueying Liu, Rebecca J. Burkhalter, Francoise Marga et al.
      Pages 319-334
    7. Hilary A. Kenny, Songuel Dogan, Marion Zillhardt, Anirban K. Mitra, S. Diane Yamada, Thomas Krausz et al.
      Pages 335-351

About this book


Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined, due to a continued inability to achieve detection of early (rather than advanced) stage disease and the lack of effective tumor-specific therapeutics.

Ovarian carcinogenesis, invasion, and metastatic dissemination require a complex cascade of interrelated genetic, molecular, and biochemical events that regulate the neoplastic transition of normal ovarian surface epithelium.

This second edition includes exciting new advances in ovarian cancer detection and treatment and provides an analysis of current research into aspects of malignant transformation, growth control, and metastasis. A more detailed understanding of these processes may ultimately translate into the development of novel approaches for the detection and control of ovarian cancer.

"Ovarian Cancer prevention, detection and treatment remain a significant health care challenge. In this text thought leaders in the field address the critical biologic and clinical issues relevant to the disease. A comprehensive spectrum of topics is covered providing up to date information on scientific discoveries and management considerations."

Steven T. Rosen, M.D.


Biomarkers Carcinom Cell Adhesion in Ovarian Cancer Epigenetics Genes Staging Tumor

Editors and affiliations

  • M. Sharon Stack
    • 1
  • David A. Fishman
    • 2
  1. 1.School of MedicineUniversity of MissouriColumbiaU.S.A.
  2. 2.School of MedicineNew York UniversityNew YorkU.S.A.

Bibliographic information

  • Book Title Ovarian Cancer
  • Book Subtitle Second Edition
  • Editors M. Sharon Stack
    David A. Fishman
  • Series Title Cancer Treatment and Research
  • Series Abbreviated Title Cancer Treatment,Research
  • DOI
  • Copyright Information Springer-Verlag US 2010
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-0-387-98093-5
  • Softcover ISBN 978-1-4614-2473-4
  • eBook ISBN 978-0-387-98094-2
  • Series ISSN 0927-3042
  • Edition Number 2
  • Number of Pages XVI, 408
  • Number of Illustrations 12 b/w illustrations, 32 illustrations in colour
  • Topics Oncology
    Cancer Research
    Human Genetics
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology


From the reviews of the second edition:

“This is a book for basic scientists and clinicians that addresses the pertinent translational and basic science issues concerning ovarian cancer. It is insightful and written at the highest level. … It is intended for basic scientists and clinicians who have questions surrounding the issues around ovarian cancer. … This outstanding and readable book covers many of the basic science and translational science issues involved in ovarian cancer.” (David G. Mutch, Doody’s Review Service, April, 2011)