The Sarcomere and Skeletal Muscle Disease

  • Nigel G. Laing

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 642)

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Elisabeth Ehler, Mathias Gautel
    Pages 1-14
  3. Kathryn N. North, Nigel G. Laing
    Pages 15-27
  4. Katarina Pelin, Carina Wallgren-Pettersson
    Pages 28-39
  5. Mai-Anh T. Nguyen, Edna C. Hardeman
    Pages 66-77
  6. Anders Oldfors, Phillipa J. Lamont
    Pages 78-91
  7. Bjarne Udd
    Pages 99-115
  8. Duygu Selcen, Olli Carpén
    Pages 116-130
  9. Lev G. Goldfarb, Montse Olivé, Patrick Vicart, Hans H. Goebel
    Pages 131-164
  10. John Sparrow, Simon M. Hughes, Laurent Segalat
    Pages 192-206
  11. Back Matter
    Pages 225-228

About this book


Although best known for its role in heart disease, the sarcomere--the fundamental unit of muscle contraction--is also involved in skeletal muscle diseases. Chapters in The Sarcomere and Skeletal Muscle Disease provide an up-to-date review of diseases caused by mutated proteins in the different sub-compartments of the sarcomere, document the techniques currently being used to investigate the pathobiological bases of the diseases, which remain largely unknown, and discuss possible therapeutic options.


biology membrane muscle pathology pathophysiology physiology proteins skeletal muscle tissue

Editors and affiliations

  • Nigel G. Laing
    • 1
  1. 1.Centre for Medical ResearchUniversity of Western Australia, Western Australian Institute for Medical ResearchNedlandsAustralia

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