© 2009

Safety of Nanoparticles

From Manufacturing to Medical Applications

  • Thomas J. Webster
  • First detailed presentation of a key issue in nanotechnology and nanomedicine

  • Of interest to researchers in both nanotechnology/nanomaterials and medicine

  • Presents safety issues as an outgrowth of research into cellular responses to nanoparticles


Part of the Nanostructure Science and Technology book series (NST)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Yuhui Jin, Xiaojun Zhao
    Pages 19-31
  3. Xiaohong Wei, Yong-kyu Lee, Kang Moo Huh, Sungwon Kim, Kinam Park
    Pages 63-88
  4. G. L. Prasad
    Pages 89-109
  5. Tatsuhiro Ishida, Hiroshi Kiwada
    Pages 111-130
  6. Samantha A. Meenach, Kimberly W. Anderson, J. Zach Hilt
    Pages 131-157
  7. Amanda M. Schrand, Jay Johnson, Liming Dai, Saber M. Hussain, John J. Schlager, Lin Zhu et al.
    Pages 159-187
  8. Andrew Z. Wang, Frank X. Gu, Omid C. Farokhzad
    Pages 209-235
  9. Back Matter
    Pages 237-239

About this book


"Environmental safety and health has become an existential issue for the nanotechnology movement, and the international community is responding to this challenge with major multi-disciplinary research efforts. This compilation covers both the toxicology and biomedical applications of nanomaterials in a form that will be a useful reference and starting point for people working in or entering this rapidly growing field."
--Dr. Robert Hurt, Director, The Institute for Molecular and Nanoscale Innovation (IMaNI) at Brown University, Professor, Brown University, Providence, RI 02917 USA


In spite of the potential use of nanomaterials as tissue engineering devices, implants, biosensors, drug delivery devices, etc., there has yet to be a compilation of the risks associated with the in vivo use of nanomaterials. There are numerous and well-known risks because of the size of nanoparticles. For example, nanoparticles can cross cell membranes and enter the cytoplasm undetected. The aim of this book is to provide one of the first detailed overviews of how cells and tissues in the body deal with nanoparticles. This is important not only for implantable devices, but also for the manufacturing of nanophase materials when particles can be inhaled or enter the body through the skin. Only by compiling research at the intersection of nanoparticles and biological processes can we determine if nanophase materials are safe to be manufactured, handled, and/or implanted for various medical applications.


Biosensor Tissue Engineering Toxicology biomedical application biomedical applications cells composite diagnosis liposomes nanomaterial nanoparticle nanophase materials safety sensors tissue

Editors and affiliations

  • Thomas J. Webster
    • 1
  1. 1.School of EngineeringBrown UniversityProvidenceUSA

Bibliographic information

Industry Sectors
Oil, Gas & Geosciences


From the reviews:

"This book provides an interdisciplinary background, a valuable reference source, and a concise summary of the state of the art of various aspects of the field… While collectively covering some of the broad issues, each article provides details of specific nanoparticles, interactions, or applications."  – Hugh J. Byrne, Analytical and Bioanalytical Chemistry, September, 2009