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Sunlight, Vitamin D and Skin Cancer

  • Jörg Reichrath

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 624)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Johan Moan, Arne Dahlback, Alina Carmen Porojnicu
    Pages 86-88
  3. Johan Moan, Alina Carmen Porojnicu, Arne Dahlback
    Pages 104-116
  4. Marianne Berwick, Anne Lachiewicz, Claire Pestak, Nancy Thomas
    Pages 117-124
  5. Rüdiger Greinert, Eckhard W. Breitbart, Peter Mohr, Beate Volkmer
    Pages 125-136
  6. Guido Bens
    Pages 137-161
  7. Diana Santo Domingo, Elma D. Baron
    Pages 187-202
  8. Cornelia S. L. Mueller, Jörg Reichrath
    Pages 215-226
  9. Melanie A. Carless, Lyn R. Griffiths
    Pages 227-240
  10. Mar Pons, Pablo Mancheño-Corvo, Pilar Martín-Duque, Miguel Quintanilla
    Pages 252-264
  11. Cara L. Benjamin, Vladislava O. Melnikova, Honnavara N. Ananthaswamy
    Pages 265-282
  12. Peter Erb, Jingmin Ji, Erwin Kump, Ainhoa Mielgo, Marion Wernli
    Pages 283-295
  13. Knuth Rass, Wolfgang Tilgen
    Pages 296-318
  14. Back Matter
    Pages 319-323

About this book

Introduction

UV exposuie represents the most important risk factor for the development of nonmelanoma skin cancer. Additionally, assessment of sun exposure parameters has consistently shown an association between the development of malignant melanoma and short term, intense UV exposure, particularly burning in childhood. As a consequence, protection of the skin from UV exposure is an integral part of skin cancer prevention programs. However, more chronic, less intense UV exposure has not been found to be a risk factor for melanoma and in fact has been found in some studies to be protective. Moreover, 90% of all requisite vitamin D is formed within the skin through the action of the sun—a serious problem—for a connection between vitamin D deficiency and various types of cancer (e. g. , colon, prostate and breast cancers) has been demonstrated in a large number of studies. Hence, the - sociation between vitamin D deficiency and various internal malignancies has now opened a debate among dermatologists and other clinicians how to balance between positive and negative effects of solar and artificial UV exposure. The goal of this volume is to provide a comprehensive, highly readable overview of our present knowledge of positive and negative effects of UV exposure, with a focus on vitamin D and skin cancer.

Keywords

apoptosis cancer carcinoma cell cytogenetics endocrinology epidemiology genetics histology melanoma molecular biology mortality pathology prevention skin cancer

Editors and affiliations

  • Jörg Reichrath
    • 1
  1. 1.Clinic for Dermatology, Venerology and AllergologyThe Saarland University HospitalHomburg/SaarGermany

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