© 2008

Actin-Binding Proteins and Disease

  • Cristobal G. dos Remedios
  • Deepak Chhabra

Part of the Protein Reviews book series (PRON, volume 8)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Actin

    1. Deepak Chhabra, Cristobal G. dos Remedios
      Pages 1-15
    2. John C. Sparrow, Nigel G. Laing
      Pages 16-36
    3. Filip Braet, Lilian Soon, Katrien Vekemans, Pall Thordarson, Ilan Spector
      Pages 37-49
    4. Ian R. Mackay, Roberto Martinez-Neira, Senga Whittingham, Dan Nicolau, Ban-Hock Toh
      Pages 50-64
  3. Actin-Binding Proteins

    1. Michael T. Maloney, Andrew W. Kinley, Chi W. Pak, James R. Bamburg
      Pages 83-187
    2. Leslie D. Burtnick, Robert C. Robinson
      Pages 188-199
    3. Pierre D. J. Moens
      Pages 200-217
    4. Joshua K. Au, Mira Krendel, Daniel Safer, Enrique M. De La Cruz
      Pages 218-228
  4. Actin-Binding Proteins

    1. Marleen Van Troys, Joël Vandekerckhove, Christophe Ampe
      Pages 229-277
    2. C. G. dos Remedios, Neil J. Nosworthy
      Pages 290-297
    3. Maurizio Stefani, Masako Tsubakihara, Brett D. Hambly, Choon C. Liew, Paul D. Allen, Peter S. Macdonald et al.
      Pages 318-334
  5. Back Matter
    Pages 335-348

About this book


This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin ¾4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a chapter that describes how intracellular pathogens use the host actin cytoskeleton. This seminal volume is intended for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.


Immune System Migration cell division cellular processes gene expression intracellular pathogens leukocytes proteins

Editors and affiliations

  • Cristobal G. dos Remedios
    • 1
  • Deepak Chhabra
    • 2
  1. 1.Muscle Research Unit Bosch Institute, School of Medical SciencesThe University of SydneySydneyAustralia
  2. 2.Discipline of Anatomy and Histology Bosch Institute, School of Medical SciencesThe University of SydneySydneyAustralia

Bibliographic information

Industry Sectors
Health & Hospitals