© 2008

Pancreatic Cancer

  • Andrew M. Lowy
  • Steven D. Leach
  • Philip A. Philip


  • Pancreatic Cancer brings to the forefront the most current advances that have been made in understanding pancreatic cancer development and successfully treating this dreadful disease.

  • This volume provides information on the recent progress and improvements to date, including developments in molecular events, landmark clinical trials, the first mouse models, and targeted biologic therapies.


Part of the M. D. Anderson Solid Tumor Oncology Series book series (MDA)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Molecular Pathology and Epidemiology

    1. N. Volkan Adsay, Duangpen Thirabanjasak, Deniz Altinel
      Pages 3-26
    2. Eric S. Calhoun, Scott E. Kern
      Pages 27-39
    3. Ralph H. Hruban, Kieran Brune, Noriyoshi Fukushima, Anirban Maitra
      Pages 41-51
    4. James G. Kench, Peter H. Cosman, Neil D. Merrett, Andrew V. Biankin
      Pages 53-64
    5. Kieran A. Brune, Alison P. Klein
      Pages 65-79
    6. Julia B. Greer, Narcis O. Zarnescu, David C. Whitcomb
      Pages 81-96
  3. Pancreatic Cancer Biology

    1. Solomon Afelik, Jan Jensen
      Pages 99-116
    2. L. Charles Murtaugh, Jared Cassiano, Jean-Paul De La O
      Pages 117-135
    3. Laleh G. Melstrom, Paul J. Grippo
      Pages 137-158
    4. Genevieve M. Boland, Sarah P. Thayer
      Pages 181-228
  4. Pancreatic Cancer Staging

    1. Haydee Ojeda-Fournier, K. Ann Choe
      Pages 255-270
    2. M. Fernandez-Ulloa
      Pages 271-283
    3. William R. Brugge
      Pages 285-294
    4. Matthew H. Katz, Abdool R. Moossa, Michael Bouvet
      Pages 295-310
  5. Surgery for Pancreatic Cancer

    1. L. Andrew Shirley, Charles J. Yeo
      Pages 313-327
    2. Thomas Schnelldorfer, Kaye M. Reid Lombardo, Michael B. Farnell, Michael G. Sarr
      Pages 329-339
    3. Andrew S. Resnick, Jeffrey A. Drebin
      Pages 341-350

About this book


Since the first M. D. Anderson Solid Tumor Oncology Series volume on pancreatic cancer, there have been major advances in our understanding of molecular events which underlie pancreatic cancer development, both in the sporadic and inherited forms. We have seen the development of the first mouse models that accurately recapitulate features of the human disease. Several landmark clinical trials in both resectable and metastatic pancreatic cancer have been completed, raising new questions about the standard of care in this disease.

Finally, the era of targeted biologic therapies has engendered new excitement about the prospects of more rapid progress in understanding and successfully treating this dreadful disease. Therefore, it is an appropriate time to review these important advances and outline areas of controversy and question in pancreatic cancer biology and treatment.


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Editors and affiliations

  • Andrew M. Lowy
    • 1
  • Steven D. Leach
    • 2
  • Philip A. Philip
    • 3
  1. 1.University of California San DiegoLa JollaUSA
  2. 2.School of MedicineJohns Hopkins UniversityBaltimoreUSA
  3. 3.Wayne State UniversityDetroitUSA

Bibliographic information

  • Book Title Pancreatic Cancer
  • Editors Andrew M. Lowy
    Steven D. Leach
    Philip Philip
  • Series Title M. D. Anderson Solid Tumor Oncology Series
  • DOI
  • Copyright Information Springer-Verlag US 2008
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-0-387-69250-0
  • Softcover ISBN 978-1-4899-7761-8
  • eBook ISBN 978-0-387-69252-4
  • Edition Number 1
  • Number of Pages XVIII, 744
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Oncology
    Surgical Oncology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology


From the reviews:

"The summary of models of pancreatic cancer is simple and would be valuable for readers who are beginning to work in the field. The review of studies in molecular signaling, genomics, and proteomics is a comprehensive introduction for clinicians who are interested in the biology of this disease. … provide a very good introduction for the clinician or the young investigator who is interested in the subject. … Clinician-investigators would be well served to read this as a review … ." (Murray F. Brennan, The New England Journal of Medicine, April, 2009)