© 2008

Mouse Models of Human Blood Cancers

Basic Research and Pre-clinical Applications

  • Shaoguang Li

Table of contents

About this book


Although it remains an open question among some people whether mice and humans are similar in disease development, the laboratory mouse has emerged as the preeminent animal model for human diseases. This is underscored by the recently completed mouse and human genome projects, which have revealed that mice and humans share the vast majority of their genes, and thus get many of the same diseases, and for the same reasons. Emphasizing why mouse models are valuable in vivo systems for understanding disease mechanisms and developing therapeutic strategies for human blood cancers, "Mouse Models of Human Blood Cancers: Basic Research and Pre-clinical Applications," edited by Shaoguang Li, aims on presenting thorough analyses of the pathological features and the molecular bases of several major types of blood cancer and to describe translational research using mouse cancer models.


DNA Hematopoietic Laboratory Microarray Myeloproliferative disease development gene expression genes human blood cancers immune-compromised mice leukemia mice mouse modeling oncogenesis

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  • Shaoguang Li

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